Clinical Trials Browser

Non Small Lung Cancer

NCT06333678 2026-01-29

A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

Phase 2 Completed

10 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05054725 2026-01-06

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Phase 2 Completed

47 enrolled 17 charts

Thoracic

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Respiratory Tract Diseases, Respiratory Tract Neoplasms

NCT04625647 2025-12-05

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Phase 2 Active not recruiting

116 enrolled

Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04933695 2025-10-22

CodeBreaK201

Phase 2 Completed

42 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05118854 2025-10-20

A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation

Phase 2 Recruiting

27 enrolled

Thoracic

Lung Neoplasms

NCT05631249 2025-05-08

CODEBREAK-IGR

Phase 2 Recruiting

40 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05398094 2025-04-10

MERIT-lung

Phase 2 Recruiting

19 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06068153 2024-11-20

AMBER

Phase 2 Withdrawn

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05815186 2024-03-29

Ladarixin With Sotorasib in Advanced NSCLC - Phase II

Phase 2 Withdrawn

Thoracic

Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation

NCT05311709 2023-11-09

SOLUCOM

Phase 2 Unknown

100 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT05400577 2023-07-17

Sotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLC

Phase 2 Withdrawn

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05451056 2022-07-11

breakthrough

Phase 2 Unknown

37 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

Clinical Trials

A Study of Sotorasib in People With Non-Small Cell Lung Cancer

A Study Comparing Sotorasib With Durvalumab in People With Non-Small Cell Lung Cancer (NSCLC)

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

CodeBreaK201

A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation

CODEBREAK-IGR

MERIT-lung

AMBER

Ladarixin With Sotorasib in Advanced NSCLC - Phase II

SOLUCOM

Sotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLC

breakthrough