Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Thyroid Carcinoma, Anaplastic

NCT00753714 2016-10-17

ZELIG

Phase 2 Completed

124 enrolled 11 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT00597116 2016-10-10

An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma

Phase 2 Terminated

25 enrolled 8 charts

Other solid neoplasmThoracic

Mesothelioma, Recurrence

NCT00777179 2016-10-10

Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet Chemotherapy

Phase 2 Completed

117 enrolled 15 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00312377 2016-09-30

ZODIAC

Phase 3 Completed

1,690 enrolled 15 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00404924 2016-09-30

ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures

Phase 3 Completed

1,140 enrolled 12 charts

Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Carcinoma, Large Cell

NCT00807170 2016-08-29

Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases

Phase 1 Terminated

5 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00496275 2016-08-26

Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLC

Phase 1 Completed

17 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00047840 2016-08-25

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.

Phase 2 Completed

129 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00071188 2016-08-25

ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Phase 2 Completed

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00252746 2016-08-25

ZD6474 Phase IIa Dose Finding Multicentre Study

Phase 2 Completed

53 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00506051 2016-08-25

ZD6474(Vandetanib) + Alimta Combo Study

Phase 1 Completed

21 enrolled

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00059722 2016-08-24

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

Phase 2 Completed

160 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00066313 2016-08-24

ZD6474 in Treating Patients With Small Cell Lung Cancer

Phase 2 Completed

Thoracic

Lung Neoplasms

NCT00290537 2016-05-19

Phase II Study of ZD6474 in Advanced NSCLC

Phase 2 Terminated

4 enrolled 3 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00402896 2016-03-09

Malignant Pleural Effusion With ZD6474

Phase 2 Terminated

28 enrolled 5 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT01004419 2015-10-02

Trial of ZD6474 and Faslodex in Non-Small Cell Lung Cancer

Phase 1 Withdrawn

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00410189 2015-03-23

BATTLE Program: ZD6474 in Previously Treated Subjects With NSCLC

Phase 2 Completed

54 enrolled 8 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00734890 2012-03-16

Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma

Phase 1 Completed

18 enrolled

DermatologicLymphoidOther hematologic neoplasmThoracic

Adenocarcinoma of Lung, Burkitt Lymphoma, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Intraocular Lymphoma

Clinical Trials

ZEAL

SAFIR02_Lung

A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)

Vandetanib in Advanced NSCLC With RET Rearrangement

Cisplatin + Etoposide +/- Concurrent ZD6474 in Previously Untreated Extensive Stage Small Cell Lung Cancer

Vandetanib, Carboplatin, and Paclitaxel in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Can Be Removed by Surgery

Radiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)

Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer

Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy

S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors

ZELIG

An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma

Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet Chemotherapy

ZODIAC

ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures

Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases

Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLC

This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer.

ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

ZD6474 Phase IIa Dose Finding Multicentre Study

ZD6474(Vandetanib) + Alimta Combo Study

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

ZD6474 in Treating Patients With Small Cell Lung Cancer

Phase II Study of ZD6474 in Advanced NSCLC

Malignant Pleural Effusion With ZD6474

Trial of ZD6474 and Faslodex in Non-Small Cell Lung Cancer

BATTLE Program: ZD6474 in Previously Treated Subjects With NSCLC

Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma