Clinical Trials

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT07458347 2026-05-12

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

GastrointestinalGynecologicThoracic

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07561723 2026-05-12

IMP3-saRNA Vaccine in Advanced NSCLC

9 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05615142 2026-05-11

Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.

9 enrolled

NSCLC

NCT02206334 2026-05-07

Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer

BreastGenitourinaryThoracic

42 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Prostatic Neoplasms, Breast Neoplasms, Male

NCT05401110 2026-05-07

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

60 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06800339 2026-05-06

NEORADJUVANT

18 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03025256 2026-05-05

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

75 enrolled

DermatologicThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

NCT06909201 2026-05-05

Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity

70 enrolled

Lung Neoplasms

NCT07249879 2026-05-01

This Study is an Open-lable, Early Study to Evaluate the Safety, Feasibility, Cytokinetics, and Preliminary Efficacy of GC511B in DLL3+ Relapsed/Refractory Small Cell Lung Cancer.

55 enrolled

Small Cell Lung Carcinoma

NCT04073745 2026-04-30

Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer

50 enrolled

Margins of Excision, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02495896 2026-04-29

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

GastrointestinalHead & NeckThoracic

61 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Gallbladder Neoplasms, Pancreatic Neoplasms

NCT06732258 2026-04-29

Low-dose Radiotherapy Combined With Concurrent Chemotherapy, Toripalimab and Tifcemalimab in the Treatment of ES-SCLC

Phase 1 Withdrawn

Phase 1 Not yet recruiting

Small Cell Lung Carcinoma

NCT06743555 2026-04-28

SAVED LUNG

14 enrolled

Pathologic Complete Response, Carcinoma, Non-Small-Cell Lung

NCT05782361 2026-04-24

POTENT

19 enrolled

Phase 1 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04266730 2026-04-23

PANDA-VAC

Phase 1 Suspended

6 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Lung Neoplasms

NCT07545954 2026-04-22

DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer

20 enrolled

Small Cell Lung Carcinoma

NCT04479306 2026-04-16

Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

37 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05704634 2026-04-15

A Phase Ib Study to Evaluate the Safety and Preliminary Efficacy of IL6-receptor Antibody Sarilumab in Combination With antiPD1 Antibody Cemiplimab for Patients With Non-small Cell Lung Cancer.

56 enrolled

Lung Neoplasms

NCT01118676 2026-04-14

Cilengitide Together With Radiochemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer

14 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03236935 2026-04-09

Phase Ib of L-NMMA and Pembrolizumab

DermatologicHead & NeckThoracic

12 enrolled 15 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma, DNA Repair-Deficiency Disorders

NCT05764954 2026-04-09

A Study of Tumor-Treating Fields (TTFields) in People With Lung Adenocarcinoma

25 enrolled

Adenocarcinoma of Lung

NCT06130254 2026-04-09

Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers

Other solid neoplasmThoracic

1 enrolled

Advanced Solid Tumor

NCT06080061 2026-04-07

Personalized Accelerated ChEmoRadiation (PACER) for Lung Cancer

45 enrolled

Lung Neoplasms

NCT07443020 2026-04-07

RIOT 4B

Other solid neoplasmThoracic

10 enrolled

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT01167530 2026-04-06

RAD001

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06249282 2026-04-03

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

15 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04925583 2026-04-02

MAGELLAN

38 enrolled

Lung Neoplasms

NCT03923270 2026-04-01

Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer

25 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT06807632 2026-04-01

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

24 enrolled

Small Cell Lung Carcinoma

NCT04762199 2026-03-31

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

69 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05681780 2026-03-31

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04197934 2026-03-30

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

56 enrolled

CNSThoracic

Astrocytoma, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Lung Neoplasms

NCT05254184 2026-03-30

KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC

12 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03678350 2026-03-27

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Other solid neoplasmThoracic

9 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT07495098 2026-03-27

Phase 1B Trial of Intratumoral Cisplatin for Stage IV Lung Cancer

Phase 1 Not yet recruiting

12 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04911166 2026-03-24

Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy

13 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

12 enrolled

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT04038619 2026-03-20

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

BreastDermatologicGynecologicThoracic

40 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Colitis, Diarrhea, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Urogenital Neoplasms, Uterine Neoplasms

NCT05143970 2026-03-20

CHANCES

BreastGastrointestinalGynecologicThoracic

27 enrolled

Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT04007744 2026-03-18

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

DermatologicGenitourinaryHead & NeckThoracic

36 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT04119024 2026-03-17

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

BreastCNSDermatologicEndocrineHead & NeckNETThoracic

18 enrolled

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Adenoma, Islet Cell, Melanoma, Neoplasm Metastasis, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms, Adrenocortical Carcinoma, Neuroendocrine Tumors

NCT06083454 2026-03-13

Ascorbate With Durvalumab in Non-Small Cell Lung Cancer (NSCLC)

1 enrolled