Clinical Trials

Carcinoma, Non-Small-Cell Lung

NCT03851445 2026-05-18

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Phase 2/3 Recruiting

10,000 enrolled

Phase 2/3 Active not recruiting

Previously Treated Non-Small Cell Lung Cancer

NCT05096663 2026-05-18

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

82 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03134118 2026-05-15

NIVOTHYM

55 enrolled

Thymoma

NCT06284317 2026-05-14

ADOPT-lung

290 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06686771 2026-05-12

CURB2

320 enrolled

BreastDermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung

NCT03804255 2026-05-06

Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting

Withdrawn

Breast Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT05642572 2026-05-06

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

66 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06116682 2026-05-06

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

88 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06031688 2026-05-05

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

56 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06616584 2026-05-05

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

Phase 2/3 Recruiting

378 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05522660 2026-04-27

USZ-STRIKE

180 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05673187 2026-04-27

ADEPPT

68 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT05633602 2026-04-17

Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study

838 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06931717 2026-04-14

ARCH

390 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02764086 2026-04-13

INTENSE: A Phase I/II Study of INhomogeneous Targeted Dose Escalation in Non-Small CEll Lung Cancer

Phase 1/2 Terminated

6 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03939481 2026-04-13

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

Active not recruiting

1,336 enrolled

GynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Ovarian Neoplasms

NCT06769126 2026-03-30

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

900 enrolled

Small Cell Lung Carcinoma

NCT04268550 2026-03-23

Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)

124 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04093167 2026-03-11

Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer

Phase 2/3 Recruiting

230 enrolled

Lung Neoplasms

NCT03057106 2026-03-03

Durvalumab and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous NSCLC

301 enrolled 15 charts

Lung Cancer Metastatic

NCT06219317 2026-02-23

ICARS

136 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05714891 2026-02-12

Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer

4 enrolled

NSCLC

NCT03965468 2026-02-09

CHESS

96 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03133546 2026-02-06

BOOSTER

155 enrolled 23 charts

Non Small Cell Lung Cancer Metastatic

NCT05718323 2026-02-06

RAISE

44 enrolled

Phase 2 Not yet recruiting

SCLC,Extensive Stage

NCT07393555 2026-02-06

Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial)

117 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05601973 2026-01-21

AMAZE-lung

60 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT07347977 2026-01-16

LidCRM

1,400 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02201992 2025-12-19

Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)

166 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04625647 2025-12-05

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

116 enrolled

Phase 2 Not yet recruiting

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07234877 2025-11-19

A Randomized Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC

158 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03694002 2025-10-30

Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery

21 enrolled 17 charts

Other solid neoplasmThoracic

Thymoma

NCT02863055 2025-09-19

NEMO

Phase 2 Terminated

37 enrolled

Mesothelioma, Malignant

NCT01770418 2025-09-09

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

Phase 1/2 Active not recruiting

32 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT07130032 2025-08-19

reICB

Other solid neoplasmThoracic

90 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT02214134 2025-08-17

SPECTAlung

Completed

539 enrolled

Mesothelioma, Malignant, Lung Neoplasms

NCT02273375 2025-08-12

Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC

Phase 3 Active not recruiting

1,415 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01726309 2025-07-08

Single Nucleotide Polymorphism(SNP)Study. ICORG 08-40, V4

Terminated

161 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT04155034 2025-05-25

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

668 enrolled

Small Cell Lung Carcinoma

NCT03845296 2025-05-21

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

64 enrolled 17 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04375904 2025-05-02

SOURCE Lung

68 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03445000 2025-04-08

ALERT-lung

Phase 2 Terminated

14 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT01753414 2025-01-06

POSTILV

Phase 2 Unknown

44 enrolled 20 charts

520 enrolled 16 charts 1 FDA

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02784171 2024-12-10

Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma

Phase 2/3 Completed

Other solid neoplasmThoracic

Mesothelioma

NCT06068153 2024-11-20

AMBER

Phase 2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT02046733 2024-11-08

STIMULI

222 enrolled 18 charts

Diabetes Mellitus, Insulin-Dependent, 12, Small Cell Lung Carcinoma

NCT04127110 2024-11-05

ALKALINE

68 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05718297 2024-10-08

BOUNCE

Phase 2 Withdrawn