Announcements Trials
Browse Landscape

Phase

Phase 1 6Phase 1/2 1

Status

Completed 4Active not recruiting 2Withdrawn 1

Sponsor Class

INDUSTRY 4NIH 2OTHER 1

Study Type

Interventional 7Expanded_access 1

Sponsor

Cancer Type

Lymphoid 38Breast 11Tumor-Agnostic 7Other hematologic neoplasm 6Gynecologic 5Genitourinary 5Gastrointestinal 5Plasma cell 4Head & Neck 4Thoracic 3CNS 3Sarcoma 2Dermatologic 2Other solid neoplasm 1Myeloid 1Endocrine 1Classical hematology 1

Conditions

Neoplasm Metastasis 4Neoplasms 3

Interventions

pembrolizumab 94Paclitaxel 85Gemcitabine 83Carboplatin 79Docetaxel 60Cisplatin 58Bevacizumab 58Nivolumab 56Fluorouracil 47Capecitabine 46Magnetic Resonance Spectroscopy 44Radiotherapy 41Irinotecan 40Oxaliplatin 38Erlotinib Hydrochloride 37Pemetrexed 34Leucovorin 34Biopsy 34atezolizumab 33Cetuximab 32Standard of Care 31Trastuzumab 28Cyclophosphamide 28Radiosurgery 27Blood Specimen Collection 27Specimen Handling 26Sorafenib 26Ipilimumab 26Everolimus 26olaparib 24

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Interventional × copanlisib × Tumor-Agnostic × Clear all
NCT03842228 2026-05-29

COD

National Cancer Institute (NCI)

Phase 1 Active not recruiting
39 enrolled 15 charts
Tumor-Agnostic

Neoplasm Metastasis

NCT04317105 2026-05-13

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
54 enrolled
Tumor-Agnostic

Neoplasm Metastasis

NCT03517956 2022-07-14

ROCOCO

Bayer

Phase 1 Completed
16 enrolled
Tumor-Agnostic

Neoplasm Metastasis

NCT05010096 2022-05-27

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

M.D. Anderson Cancer Center

Phase 1 Withdrawn
Tumor-Agnostic

Neoplasm Metastasis

NCT01411410 2017-10-11

Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced Cancer

Bayer

Phase 1 Completed
55 enrolled
Tumor-Agnostic

Neoplasms

NCT00962611 2017-10-06

BAY80-6946 Open Label, Phase I Study in Patients With Advanced Cancer

Bayer

Phase 1 Completed
57 enrolled
Tumor-Agnostic

Neoplasms

NCT01392521 2015-04-17

Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer

Bayer

Phase 1 Completed
64 enrolled
Tumor-Agnostic

Neoplasms

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