Clinical Trials

Carcinoma, Squamous Cell

NCT04958239 2026-04-14

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

151 enrolled

Neoplasms

NCT05382559 2026-04-14

A Study of ASP3082 in Adults With Advanced Solid Tumors

681 enrolled

Neoplasm Metastasis, Neoplasms

NCT03030378 2026-04-13

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

36 enrolled

Neoplasm Metastasis

NCT04520711 2026-04-13

Hotspot TCR-T: A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)

24 enrolled

Carcinoma

NCT04799054 2026-04-13

A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

188 enrolled

Neoplasm Metastasis

NCT07247110 2026-04-13

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

250 enrolled

Phase 2 Active not recruiting

Neoplasms

NCT04847466 2026-04-08

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

18 enrolled

Neoplasms

NCT06901531 2026-04-03

LUCERNA

Phase 3 Recruiting

500 enrolled

Adenocarcinoma, Neoplasms

NCT03899155 2026-04-01

Pan Tumor Rollover Study

1,500 enrolled

Neoplasms

NCT06031233 2026-03-30

MINUTE

Phase 4 Recruiting

776 enrolled

Neoplasms

NCT06188208 2026-03-30

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

Phase 1 Terminated

132 enrolled

Neoplasms

NCT03568058 2026-03-24

Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers

25 enrolled 12 charts

Neoplasms

NCT05027633 2026-03-20

Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)

Carcinoma, Squamous Cell

NCT04443088 2026-03-18

KEYNOTE-E12

78 enrolled

Neoplasm Metastasis, Neoplasms

NCT03833167 2026-03-10

KEYNOTE-630

Phase 3 Completed

450 enrolled 18 charts

Carcinoma, Squamous Cell

NCT03976362 2026-02-25

KEYLYNK-008

Phase 3 Completed

851 enrolled 25 charts

Phase 2 Active not recruiting

Carcinoma

NCT04150900 2026-02-19

1922GCCC: Pembro and Bavituximab for Squamous Cell Carcinoma of Head and Neck

7 enrolled 11 charts

Carcinoma, Squamous Cell

NCT05365581 2026-02-13

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

398 enrolled

Phase 1 Not yet recruiting

Adenocarcinoma

NCT07404332 2026-02-11

5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors

Phase 3 Active not recruiting

Neoplasm Metastasis

NCT03768063 2026-01-29

IMbrella B

1,000 enrolled

Neoplasms

NCT04260529 2026-01-29

CICILIA

Phase 1/2 Completed

60 enrolled 18 charts

Neoplasms

NCT03752333 2026-01-22

CUPem

Phase 2 Completed

Neoplasms, Unknown Primary

NCT05273554 2026-01-12

A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma

15 enrolled

Phase 2 Active not recruiting

Adenocarcinoma, Neoplasms

NCT04795661 2026-01-07

IMHOTEP

240 enrolled

Neoplasms

NCT02560636 2026-01-06

PLUMMB

34 enrolled

Neoplasm Metastasis

NCT07197827 2025-12-24

A Study of YL242 in Subjects With Advanced Solid Tumors

Phase 1/2 Recruiting

424 enrolled

Neoplasms

NCT05270213 2025-12-19

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

164 enrolled

Neoplasm Metastasis, Neoplasms

NCT06551142 2025-12-18

PanTumor-101

590 enrolled

Neoplasms

NCT05165433 2025-12-16

FORTIFY

14 enrolled

Carcinoma, Neoplasm Metastasis

NCT06108050 2025-12-16

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

177 enrolled

Neoplasm Metastasis

NCT04009681 2025-12-15

HAMMER

175 enrolled

Phase 1 Not yet recruiting

Neoplasm Metastasis, Neoplasms

NCT06724042 2025-12-10

Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors

159 enrolled

Neoplasm Metastasis

NCT05338658 2025-12-09

Study of PAT in Patients With Solid Tumor Cancers

21 enrolled

Neoplasm Metastasis

NCT07021898 2025-12-03

BOREALIS-1

200 enrolled

Neoplasm Metastasis, Neoplasms

NCT05383170 2025-11-28

Catalyst

Phase 1/2 Completed

6 enrolled 11 charts

Neoplasms

NCT03486301 2025-11-12

EIK1001

87 enrolled

Neoplasms

NCT04840394 2025-11-12

Clinical Study of BDB018: Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

1 enrolled

Neoplasms

NCT06246110 2025-11-12

A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

70 enrolled

Neoplasm Metastasis

NCT06697301 2025-11-12

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Phase 2/3 Recruiting

740 enrolled

Neoplasm Metastasis

NCT02959437 2025-10-21

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

70 enrolled 14 charts

Neoplasm Metastasis

NCT05514444 2025-10-09

MK-4464-001

64 enrolled

Neoplasms

NCT03564691 2025-10-07

MK-4830-001

470 enrolled

Neoplasms

NCT05501821 2025-09-25

Study of KBA1412 in Participants With Advanced Solid Malignant Tumors

16 enrolled

Neoplasms

NCT06983743 2025-09-11

AURORAS-1

200 enrolled

Neoplasm Metastasis, Neoplasms

NCT06831136 2025-09-10

PANCARDINAL-2

24 enrolled

Neoplasm Metastasis, Neoplasms

NCT05378425 2025-09-09

A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab

90 enrolled

Neoplasm Metastasis, Neoplasms

NCT07018570 2025-08-26

An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma

26 enrolled

Adenocarcinoma

NCT05394103 2025-08-17

Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors

Phase 1/2 Recruiting

130 enrolled

Neoplasm Metastasis

NCT04717375 2025-08-07

Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors

125 enrolled