Announcements Trials
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Phase

Phase 2 3Phase NA 2Phase 4 1

Status

Recruiting 3Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 7OTHER 6NIH 1

Study Type

Interventional 6

Sponsor

Conditions

Breast Neoplasms 2315Neoplasms 1678Prostatic Neoplasms 1178Lung Neoplasms 908Colorectal Neoplasms 873Carcinoma, Non-Small-Cell Lung 848Leukemia, Myeloid, Acute 587Pancreatic Neoplasms 568Multiple Myeloma 542Carcinoma, Hepatocellular 510Brain Neoplasms 509Neoplasm Metastasis 456Head and Neck Neoplasms 454Melanoma 410Ovarian Neoplasms 404Glioblastoma 397Precursor Cell Lymphoblastic Leukemia-Lymphoma 390Stomach Neoplasms 370Uterine Cervical Neoplasms 355Squamous Cell Carcinoma of Head and Neck 355Rectal Neoplasms 336Recurrence 332Hematologic Neoplasms 323Sarcoma 322Colonic Neoplasms 316Lymphoma 310Triple Negative Breast Neoplasms 284Urinary Bladder Neoplasms 279Glioma 277Carcinoma, Renal Cell 277

Interventions

Osilodrostat 2Metyrapone 2Radiofrequency Ablation 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
OTHER × ACTH Syndrome, Ectopic × 1 year × Clear all
NCT02756754 2026-05-04

ADERADHTA

University Hospital, Toulouse

Phase NA Completed
31 enrolled

ACTH Syndrome, Ectopic, Hyperaldosteronism

NCT07361874 2026-03-27

IMPACT-MACS

University of Texas Southwestern Medical Center

Phase NA Recruiting
75 enrolled

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Cushing Syndrome, Insulin Resistance, Weight Loss

NCT07247058 2026-03-05

Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)

Johns Hopkins University

Phase 4 Recruiting
10 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Hypertension

NCT07104812 2026-02-11

Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)

Mayo Clinic

Phase 2 Recruiting
15 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Cushing Syndrome

NCT06106295 2025-09-22

Metyrapone for Mild Autonomous Cortisol Secretion (MACS)

Mayo Clinic

Phase 2 Active not recruiting
30 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Cushing Syndrome

NCT07138274 2025-08-22

Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS

Mayo Clinic

Phase 2 Not yet recruiting
90 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Cushing Syndrome

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