Clinical Trials Browser

Adenocarcinoma × Leucovorin × Clear all

NCT07431281 2026-04-13

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Phase 3 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT06901531 2026-04-03

LUCERNA

Phase 3 Recruiting

Adenocarcinoma, Neoplasms

NCT03504397 2026-02-13

Spotlight

Phase 3 Active not recruiting

565 enrolled 63 charts 3 FDA

Gastrointestinal

Adenocarcinoma, Neoplasms, Stomach Neoplasms

NCT05365581 2026-02-13

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Phase 1 Recruiting

Adenocarcinoma

NCT06846346 2025-11-28

GRACIE

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT03777813 2025-11-18

ARION

Phase 2 Completed

Gastrointestinal

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT04363801 2025-10-09

DisTinGuish

Phase 2 Terminated

247 enrolled 38 charts

Gastrointestinal

Adenocarcinoma, Neoplasms, Stomach Neoplasms

NCT04361708 2025-10-01

I-FLOAT

Phase 1 Recruiting

Adenocarcinoma

NCT07018570 2025-08-26

An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma

Phase 2 Recruiting

Adenocarcinoma

NCT07118800 2025-08-12

NACRE-2

Phase 3 Not yet recruiting

Adenocarcinoma

NCT04864067 2025-07-01

NOAHS-ARC

Phase 2 Active not recruiting

Gastrointestinal

Adenocarcinoma, Rectal Neoplasms

NCT02509286 2024-05-08

ESOPEC

Phase 3 Active not recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT04299880 2023-11-08

Rollover Study to Provide Continued Access to Napabucasin for Patients Enrolled in Boston Biomedical-sponsored Protocols

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Pancreatic Neoplasms

NCT05264896 2023-09-07

Perioperative FLOT vs Adjuvant XELOX for CA Stomach

Phase 3 Recruiting

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT01726582 2023-08-14

Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")

Phase 2 Completed

229 enrolled 14 charts

Gastrointestinal

Adenocarcinoma, Neoplasms, Pancreatic Neoplasms

NCT01442649 2022-01-11

Efficacy of Chemotherapy, Associated to Either Cetuximab or Bevacizumab, in KRAS Wild-type Metastatic Colorectal Cancer Patients With Progressive Disease After Receiving First-line Treatment With Bevacizumab

Phase 2 Completed

Gastrointestinal

Adenocarcinoma, Neoplasm Metastasis, Colorectal Neoplasms

NCT01660711 2021-11-08

A Pilot Study of Pre- and Post-surgery Chemotherapy With mFOLFIRINOX in Localized, Resectable Pancreatic Adenocarcinoma

Phase 2 Completed

22 enrolled 8 charts

Adenocarcinoma, Neoplasms

NCT01442935 2021-06-18

Chemotherapies Associated With Targeted Therapies on the Resection Rate of Hepatic Metastases

Phase 2 Completed

Gastrointestinal

Adenocarcinoma, Colorectal Neoplasms

NCT01652976 2021-01-05

FOLFOX-D

Phase 2 Completed

44 enrolled 18 charts

Gastrointestinal

Adenocarcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT01443065 2020-11-17

MEGA

Phase 2 Completed

Gastrointestinal

Adenocarcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT00515411 2019-12-10

Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma

Phase 2 Completed

111 enrolled 11 charts

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT02620800 2019-10-22

FABLOx

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Pancreatic Neoplasms

NCT01206530 2019-04-18

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

Phase 1/2 Completed

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT01504256 2018-01-23

CatuNeo

Phase 2 Completed

Adenocarcinoma, Peritoneal Neoplasms

NCT01383538 2017-08-08

FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Neoplasms, Pancreatic Neoplasms

NCT01472029 2017-06-19

HerFLOT

Phase 2 Completed

Adenocarcinoma

NCT00499850 2016-08-25

Phase I FOLFOX Combination

Phase 1 Completed

Adenocarcinoma

NCT00507091 2016-08-25

Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination

Phase 1 Completed

Adenocarcinoma, Neoplasm Metastasis

NCT01175291 2011-12-05

FOLFOX/Bevacizumab +/- MK-0646 in Metastatic Colorectal Cancer

Phase 2 Withdrawn

Gastrointestinal

Adenocarcinoma, Neoplasm Metastasis, Colorectal Neoplasms