Clinical Trials

Adenocarcinoma Of Esophagus, Barrett Esophagus

NCT07223424 2026-04-16

PSI-Immune

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

880 enrolled

Adenocarcinoma Of Esophagus, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Colitis, Ulcerative, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma

NCT03161522 2026-04-15

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

100 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT05745857 2026-04-13

SLURP

25 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus

NCT05677490 2026-04-07

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Phase 3 Recruiting

382 enrolled

Adenocarcinoma Of Esophagus

NCT05480384 2026-04-01

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

1 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT02366819 2026-03-30

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Phase 4 Suspended

36 enrolled

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT07282912 2026-03-04

OLIGOMETS

54 enrolled

Adenocarcinoma Of Esophagus, Cholangiocarcinoma

NCT06523374 2026-02-24

Endeavor-1

50 enrolled

BreastGastrointestinalGynecologic

Adenocarcinoma Of Esophagus, Barrett Esophagus, Esophageal Neoplasms

NCT06623396 2026-02-11

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

Phase 1 Recruiting

18 enrolled

Adenocarcinoma Of Esophagus, Breast Neoplasms, Diabetes Mellitus, Peritoneal Neoplasms

NCT00628368 2026-02-10

Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer

Phase NA Completed

160 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07375420 2026-02-02

OPTIMUS

50 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Motor Activity

NCT06824363 2026-01-30

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

34 enrolled

Adenocarcinoma Of Esophagus

NCT03961945 2026-01-26

Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma

1,550 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus, Esophageal Neoplasms, Gastroesophageal Reflux

NCT03539822 2026-01-21

CAMILLA

Phase 1/2 Recruiting

117 enrolled

Adenocarcinoma Of Esophagus, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms

NCT04028167 2026-01-09

Induction FLOT With CROSS CRT for Esophageal Cancer

40 enrolled

Adenocarcinoma Of Esophagus

NCT06161818 2025-12-22

TNT-OES-2

216 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07059299 2025-12-19

NeoTISLEGA

Phase 1 Recruiting

18 enrolled

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT06071845 2025-12-16

SOS4C

400 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus

NCT06251973 2025-12-02

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

37 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT06846346 2025-11-28

GRACIE

88 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT05753748 2025-11-24

SURVENT

680 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus

NCT06687603 2025-11-13

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

800 enrolled

Phase 2 Not yet recruiting

Adenocarcinoma Of Esophagus, Barrett Esophagus, Gastroesophageal Reflux

NCT07222657 2025-10-31

Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma

40 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT04221893 2025-10-06

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

28 enrolled

Adenocarcinoma Of Esophagus, Anal Canal Carcinoma, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms

NCT05051475 2025-10-03

RATE

Phase NA Completed

62 enrolled

Phase 1/2 Active not recruiting

Adenocarcinoma Of Esophagus, Barrett Esophagus, Gastroesophageal Reflux

NCT02962063 2025-09-05

Durvalumab, an Anti-PDLI Antibody, and Tremelimumab, an Anti-CTLA4 Antibody, and Chemoradiation Before Surgery for Esophageal Cancer

64 enrolled

Adenocarcinoma Of Esophagus

NCT04929392 2025-09-04

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

3 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma

NCT06687876 2025-07-10

MEMENTO

14 enrolled

Phase 2 Not yet recruiting

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT06933966 2025-04-18

ATTENUATION

120 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT03429816 2025-03-27

OPPOSITE

Phase NA Completed

120 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT04802876 2025-03-21

ACROPOLI

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

184 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04114136 2025-02-10

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

DermatologicGastrointestinalHead & Neck

72 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hepatocellular, Melanoma

NCT03366012 2024-11-08

REACT

Phase NA Terminated

51 enrolled 4 charts

Adenocarcinoma Of Esophagus, Barrett Esophagus, Gastroesophageal Reflux

NCT05476796 2024-10-24

LOGICAN

118 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Recurrence

NCT05713838 2024-09-19

Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery

32 enrolled

Adenocarcinoma Of Esophagus

NCT01404156 2024-08-28

POWERRANGER

Phase 2/3 Completed

29 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT05177133 2024-08-02

AuspiCiOus

25 enrolled

Adenocarcinoma Of Esophagus, Microsatellite Instability

NCT03641547 2024-07-18

CHARIOT

Phase 1 Completed

36 enrolled 24 charts

Adenocarcinoma Of Esophagus, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT05530343 2024-06-12

SWAT-BE

2,298 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus

NCT04159974 2024-05-09

RICE

Phase 2 Unknown

56 enrolled

Phase 3 Active not recruiting

Adenocarcinoma Of Esophagus

NCT02509286 2024-05-08

ESOPEC

438 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Esophageal Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts