Announcements Trials
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Phase

Phase 2 3Phase 3 2

Status

Completed 5

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 5

Conditions

Carcinoma, Non-Small-Cell Lung 16Lung Neoplasms 5Adenocarcinoma of Lung 5Neoplasms 3Lymphoma, Large-Cell, Anaplastic 3Granuloma, Plasma Cell 3Hematologic Neoplasms 2Tumors Characterized by Genetic Alterations in Anaplastic Lymphoma Kinase (ALK) 1Rhabdomyosarcoma 1Neuroblastoma 1Lymphoma, B-Cell 1Glioblastoma 1Cholangiocarcinoma 1Brain Neoplasms 1Adenocarcinoma Of Esophagus 1ALK-positive NSCLC 1ALK-positive Advanced Tumors 1

Interventions

pembrolizumab 8Pemetrexed 8capmatinib 7Carboplatin 7ceritinib 5Cisplatin 5Bevacizumab 4Docetaxel 3trametinib 2motexafin gadolinium 2aldesleukin 2Vinorelbine 2Paclitaxel 2Interleukin-2 2Gefitinib 2BID protein, human 2technetium 99m etarfolatide 1spartalizumab 1sintilimab 1satraplatin 1ribociclib 1picropodophyllin 1nazartinib 1naporafenib 1milademetan 1lazertinib 1fludarabine phosphate 1fludarabine 1farletuzumab 1enzalutamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Adenocarcinoma of Lung × ceritinib × Clear all
NCT01828112 2025-02-07

LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and Crizotinib

Novartis

Phase 3 Completed
231 enrolled 33 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01828099 2025-01-16

LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer

Novartis

Phase 3 Completed
376 enrolled 34 charts 1 FDA
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02450903 2021-03-30

LDK378 in Patients With ALK Positive NSCLC Previously Treated With Alectinib.

Novartis

Phase 2 Completed
20 enrolled 12 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02276027 2020-12-16

A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer

Novartis

Phase 2 Completed
66 enrolled 18 charts
Thoracic

Adenocarcinoma of Lung

NCT01685138 2019-03-26

LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

Novartis

Phase 2 Completed
124 enrolled 18 charts
Thoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

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