Clinical Trials

BreastDermatologicGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

11 enrolled

Adenocarcinoma of Lung, Mesothelioma, Malignant, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT02974725 2025-04-13

A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma

241 enrolled

DermatologicThoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma

NCT03371381 2025-02-04

An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung

Phase 1/2 Terminated

12 enrolled 15 charts

Adenocarcinoma of Lung

NCT05012397 2024-10-17

Milademetan in Advanced/Metastatic Solid Tumors

DermatologicEndocrineGastrointestinalGenitourinaryGynecologicSarcomaThoracic

40 enrolled 13 charts

Testicular Germ Cell Tumor, Adenocarcinoma of Lung, Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Adrenocortical Carcinoma, Cholangiocarcinoma

NCT04161391 2024-06-13

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Phase 1/2 Terminated

41 enrolled 18 charts

Head & NeckThoracic

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Thyroid Neoplasms, Carcinoma, Medullary

NCT04682431 2024-03-22

A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

BreastGastrointestinalHead & NeckThoracic

127 enrolled

Adenocarcinoma of Lung, Breast Neoplasms, Head and Neck Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04691375 2024-03-22

A Study of PY314 in Subjects With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicThoracic

86 enrolled

Adenocarcinoma of Lung, Breast Neoplasms, Carcinoma, Renal Cell, Ovarian Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT04861948 2022-10-04

IBI188 Combination Therapy in Solid Tumors

9 enrolled

SarcomaThoracic

Adenocarcinoma of Lung, Osteosarcoma

NCT03891173 2022-08-12

A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma

9 enrolled

Adenocarcinoma of Lung

NCT01646125 2019-07-24

An Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations

59 enrolled 9 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02121925 2017-09-05

ONC003

Terminated

227 enrolled

Adenocarcinoma of Lung, Lung Neoplasms

NCT02715102 2017-08-21

Circulating Tumor DNA in Patients at High Risk for Lung Cancer

Terminated

39 enrolled

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT00365183 2013-10-31

Trial of Motexafin Gadolinium and Pemetrexed (Alimta®) for Second Line Treatment in Patients With Non-Small Cell Lung Cancer

74 enrolled

Adenocarcinoma of Lung, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Carcinoma, Large Cell

NCT00093132 2012-08-17

Satraplatin for Locally Advanced Non-Small Cell Lung Cancer With Simultaneous Radiotherapy

Phase 1/2 Terminated

20 enrolled