Announcements Trials
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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 136Unspecified Adult Solid Tumor, Protocol Specific 122Leukemia, Lymphocytic, Chronic, B-Cell 119Lymphoma 103Breast Neoplasms 102Neoplasms 99Lymphoma, Follicular 98Burkitt Lymphoma 98Lymphoma, Large B-Cell, Diffuse 97Lymphoma, Non-Hodgkin 94Leukemia, Myeloid, Acute 89Lymphoma, Mantle-Cell 88Lymphoma, B-Cell, Marginal Zone 81Neoplasm Metastasis 80Lymphoma, Large-Cell, Immunoblastic 73Carcinoma, Non-Small-Cell Lung 68Melanoma 64Hodgkin Disease 64Lymphoma, T-Cell, Cutaneous 63Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 60Lymphoma, Large-Cell, Anaplastic 60Lung Neoplasms 60Prostatic Neoplasms 58Brain Neoplasms 58Astrocytoma 57Mycosis Fungoides 55Colonic Neoplasms 55Glioblastoma 54Sezary Syndrome 52Ovarian Neoplasms 52

Interventions

Dexamethasone 1Calcium Dobesilate 12,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × NIH × Adenoma, Basophil × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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