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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Leukemia, Myeloid, Acute 56Precursor Cell Lymphoblastic Leukemia-Lymphoma 45Myelodysplastic Syndromes 41Leukemia, Lymphocytic, Chronic, B-Cell 30Lymphoma, Non-Hodgkin 27Multiple Myeloma 22Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22Hodgkin Disease 20Leukemia 17Myeloproliferative Disorders 16Recurrence 15Lymphoma, Follicular 15Leukemia, Biphenotypic, Acute 15Melanoma 14Lymphoma, Mantle-Cell 14Lymphoma 14Leukemia, Myelomonocytic, Chronic 14Lymphoma, Large B-Cell, Diffuse 13Hematologic Neoplasms 13Burkitt Lymphoma 11Anemia, Refractory, with Excess of Blasts 11Lymphoma, B-Cell, Marginal Zone 10Lymphoma, B-Cell 10Primary Myelofibrosis 8Neoplasm, Residual 7Neoplasm Metastasis 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Neuroblastoma 6Neoplasms 6Graft vs Host Disease 6

Interventions

pembrolizumab 2relacorilant 1olaparib 1lutetium Lu 177 dotatate 1fludarabine phosphate 1fludarabine 1cabozantinib 1Specimen Handling 1Mesna 1Magnetic Resonance Spectroscopy 1Floxuridine 1Dexamethasone 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Adrenal Cortex Neoplasms × fludarabine phosphate × 1 year × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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