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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Leukemia, Myeloid, Acute 199Leukemia, Lymphocytic, Chronic, B-Cell 169Leukemia 165Myelodysplastic Syndromes 162Precursor Cell Lymphoblastic Leukemia-Lymphoma 151Lymphoma, Non-Hodgkin 129Lymphoma 120Multiple Myeloma 112Hodgkin Disease 110Lymphoma, Follicular 97Lymphoma, Mantle-Cell 95Lymphoma, Large B-Cell, Diffuse 87Lymphoma, B-Cell, Marginal Zone 79Myeloproliferative Disorders 77Burkitt Lymphoma 75Congenital Abnormalities 73Leukemia, Myelogenous, Chronic, BCR-ABL Positive 67Leukemia, Myelomonocytic, Chronic 66Leukemia, Myeloid, Chronic-Phase 64Leukemia, Myeloid, Accelerated Phase 62Recurrence 57Lymphoma, Large-Cell, Immunoblastic 55Waldenstrom Macroglobulinemia 50Anemia, Refractory, with Excess of Blasts 50Primary Myelofibrosis 48Neoplasms, Plasma Cell 47Blast Crisis 47Hematologic Neoplasms 40Leukemia, Prolymphocytic 37Dendritic Cell Sarcoma, Interdigitating 37

Interventions

pembrolizumab 2cabozantinib 2veliparib 1olaparib 1lutetium Lu 177 dotatate 1fludarabine phosphate 1fludarabine 1Temozolomide 1Specimen Handling 1Pharmacogenomic Variants 1Pharmacogenomic Testing 1Nivolumab 1Mesna 1Magnetic Resonance Spectroscopy 1Gefitinib 1Cyclophosphamide 1Capecitabine 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Adrenal Cortex Neoplasms × fludarabine phosphate × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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