Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 3 1Phase 1 1

Status

Recruiting 4Not yet recruiting 1

Sponsor Class

OTHER 5NETWORK 1INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 5

Conditions

Breast Neoplasms 2315Neoplasms 1678Prostatic Neoplasms 1178Lung Neoplasms 908Colorectal Neoplasms 873Carcinoma, Non-Small-Cell Lung 848Leukemia, Myeloid, Acute 587Pancreatic Neoplasms 568Multiple Myeloma 542Carcinoma, Hepatocellular 510Brain Neoplasms 509Neoplasm Metastasis 456Head and Neck Neoplasms 454Melanoma 410Ovarian Neoplasms 404Glioblastoma 397Precursor Cell Lymphoblastic Leukemia-Lymphoma 390Stomach Neoplasms 370Uterine Cervical Neoplasms 355Squamous Cell Carcinoma of Head and Neck 355Rectal Neoplasms 336Recurrence 332Hematologic Neoplasms 323Sarcoma 322Colonic Neoplasms 316Lymphoma 310Triple Negative Breast Neoplasms 284Urinary Bladder Neoplasms 279Glioma 277Carcinoma, Renal Cell 277

Interventions

defactinib 1Oxaliplatin 1Cetuximab 1Capecitabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Advanced Colorectal Cancer × 1 year × Clear all
NCT06369259 2026-05-20

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

M.D. Anderson Cancer Center

Phase 2 Recruiting
33 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT07558083 2026-04-30

FOLICOLOR

University Hospital, Antwerp

Phase 3 Recruiting
150 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT07391618 2026-02-06

Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU

Chinese PLA General Hospital

Phase 2 Recruiting
583 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT07178613 2025-09-17

Assessment of the Dose Safety and Efficacy of Serine Combined With Fluorouracil Drugs

The First Affiliated Hospital of Xinxiang Medical College

Phase 1 Not yet recruiting
20 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT06885385 2025-06-24

A Phase 2 Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer

Shanghai Junshi Bioscience Co., Ltd.

Phase 2 Recruiting
60 enrolled
Gastrointestinal

Advanced Colorectal Cancer

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