Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 3 1

Status

Recruiting 4Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Gastrointestinal 4

Conditions

Breast Neoplasms 1217Neoplasms 1027Carcinoma, Non-Small-Cell Lung 749Prostatic Neoplasms 688Colorectal Neoplasms 593Lung Neoplasms 573Pancreatic Neoplasms 394Leukemia, Myeloid, Acute 394Neoplasm Metastasis 388Ovarian Neoplasms 370Multiple Myeloma 369Stomach Neoplasms 316Carcinoma, Hepatocellular 301Melanoma 281Brain Neoplasms 277Recurrence 273Squamous Cell Carcinoma of Head and Neck 269Head and Neck Neoplasms 237Endometrial Neoplasms 234Glioblastoma 233Triple Negative Breast Neoplasms 228Uterine Cervical Neoplasms 221Precursor Cell Lymphoblastic Leukemia-Lymphoma 221Lymphoma 221Sarcoma 201Hematologic Neoplasms 199Urinary Bladder Neoplasms 196Esophageal Neoplasms 190Carcinoma, Renal Cell 188Lymphoma, Non-Hodgkin 176

Interventions

defactinib 1Oxaliplatin 1Cetuximab 1Capecitabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Recruiting × Advanced Colorectal Cancer × 1 year × Clear all
NCT06369259 2026-05-20

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

M.D. Anderson Cancer Center

Phase 2 Recruiting
33 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT07558083 2026-04-30

FOLICOLOR

University Hospital, Antwerp

Phase 3 Recruiting
150 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT07391618 2026-02-06

Clinical Study on the First-line Treatment of Advanced Colorectal Cancer With Simultaneous Infusion of Levozolinate for Injection and 5-FU

Chinese PLA General Hospital

Phase 2 Recruiting
583 enrolled
Gastrointestinal

Advanced Colorectal Cancer

NCT06885385 2025-06-24

A Phase 2 Study Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal Cancer

Shanghai Junshi Bioscience Co., Ltd.

Phase 2 Recruiting
60 enrolled
Gastrointestinal

Advanced Colorectal Cancer

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