Announcements Trials
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Phase

Phase 1 4

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Other solid neoplasm 4

Conditions

Breast Neoplasms 8Ovarian Neoplasms 6Neoplasm Metastasis 4Advanced Solid Tumors 4Triple Negative Breast Neoplasms 3Small Cell Lung Carcinoma 3Prostatic Neoplasms 3Leukemia, Myeloid, Acute 3Fallopian Tube Neoplasms 3Pancreatic Neoplasms 2Neoplasms 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Vaginal Neoplasms 1Uterine Cervical Neoplasms 1Triple Negative Metastatic Breast Cancer 1Thrombocythemia, Essential 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Solid Tumor 1Sarcoma, Ewing 1Primary Myelofibrosis 1Polycythemia Vera 1Neuroendocrine Tumors 1Myeloproliferative Disorders 1Myelodysplastic Syndromes 1Metastatic Castration Resistant Prostate Cancer (mCRPC) 1Mesothelioma 1Lymphoma, Mantle-Cell 1Lung Neoplasms 1

Interventions

Injections 18Carboplatin 14Docetaxel 11pembrolizumab 8durvalumab 7Cisplatin 6linifanib 5Paclitaxel 5Nivolumab 5zimberelimab 4talazoparib 4olaparib 4Panobinostat 4Itraconazole 4Bevacizumab 4tremelimumab 3sintilimab 3depatuxizumab 3atezolizumab 3ST 1481 3S 1 (combination) 3Rifampin 3Pemetrexed 3Oxaliplatin 3Fluorouracil 3Everolimus 3Drug Therapy 3trifluridine tipiracil drug combination 2trametinib 2toripalimab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Advanced Solid Tumors × talazoparib × Clear all
NCT03077607 2021-06-30

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors

Pfizer

Phase 1 Completed
36 enrolled 28 charts
Other solid neoplasm

Advanced Solid Tumors

NCT02997176 2021-02-25

An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)

Pfizer

Phase 1 Completed
38 enrolled 42 charts
Other solid neoplasm

Advanced Solid Tumors

NCT02997163 2021-01-05

An Open-Label Pharmacokinetics and Safety Study of Talazoparib

Pfizer

Phase 1 Completed
34 enrolled 39 charts
Other solid neoplasm

Advanced Solid Tumors

NCT03070548 2018-12-17

A Study of Talazoparib in Patients With Advanced Solid Tumors

Pfizer

Phase 1 Completed
6 enrolled 34 charts
Other solid neoplasm

Advanced Solid Tumors

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