Announcements Trials
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Phase

Phase 1 5

Status

Completed 3Terminated 2

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Other solid neoplasm 5

Conditions

Ovarian Neoplasms 6Advanced Solid Tumours 5Squamous Cell Carcinoma of Head and Neck 4Small Cell Lung Carcinoma 4Uterine Cervical Neoplasms 3Neoplasms 3Lung Neoplasms 3Leukemia, Myeloid, Acute 3Glioblastoma 3Fallopian Tube Neoplasms 3Uterine Neoplasms 2Triple Negative Breast Neoplasms 2Stomach Neoplasms 2Solid Tumors 2Prostatic Neoplasms 2Pancreatic Neoplasms 2Neoplasm Metastasis 2Multiple Myeloma 2Lymphoma 2Hematologic Neoplasms 2Esophageal Neoplasms 2Colorectal Neoplasms 2Carcinoma, Renal Cell 2Advanced Malignant Solid Neoplasm 2Vaginal Neoplasms 1Urinary Bladder Neoplasms 1Triple-negative Metastatic Breast Cancer 1Tongue Neoplasms 1Thyroid Neoplasms 1Rhabdomyosarcoma 1

Interventions

adavosertib 5durvalumab 3Paclitaxel 3olaparib 2ceralasertib 2Fluorouracil 2Carboplatin 2toripalimab 1sintilimab 1pembrolizumab 1factor IX, factor VII, factor X, prothrombin drug combination 1drug XX Z 1danvatirsen 1capivasertib 1Rifampin 1Pantoprazole 1Omeprazole 1Leucovorin 1Itraconazole 1Irinotecan 1Injections 1Gemcitabine 1Doxorubicin 1Cisplatin 1AZD0156 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Advanced Solid Tumours × adavosertib × Clear all
NCT02617277 2026-03-04

Safety, Tolerability and Pharmacokinetics of AZD1775 (Adavosertib) Plus MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumours

AstraZeneca

Phase 1 Completed
56 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT04959266 2022-09-16

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

AstraZeneca

Phase 1 Terminated
5 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT04949425 2022-09-02

A Study to Assess the Safety and Tolerability of Adavosertib for Patients With Advanced Solid Tumours

AstraZeneca

Phase 1 Terminated
3 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT04462952 2022-07-25

Study of Adavosertib(AZD1775) in Japanese Patients With Advanced Solid Tumours

AstraZeneca

Phase 1 Completed
6 enrolled
Other solid neoplasm

Advanced Solid Tumours

NCT02341456 2019-03-25

Phase Ib Study AZD1775 in Combination With Carboplatin and Paclitaxel in Adult Asian Patients With Solid Tumours

AstraZeneca

Phase 1 Completed
19 enrolled 53 charts
Other solid neoplasm

Advanced Solid Tumours

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