Announcements Trials
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Phase

Phase 1/2 2Phase 3 1Phase 2 1Phase 1 1

Status

Recruiting 3Not yet recruiting 1Completed 1Available 1

Sponsor Class

OTHER 16INDUSTRY 6

Study Type

Interventional 5Expanded_access 1

Sponsor

Cancer Type

Plasma cell 6Other hematologic neoplasm 1Lymphoid 1

Conditions

Carcinoma, Non-Small-Cell Lung 926Neoplasms 609Breast Neoplasms 604Colorectal Neoplasms 457Neoplasm Metastasis 394Ovarian Neoplasms 328Melanoma 312Prostatic Neoplasms 311Lung Neoplasms 294Multiple Myeloma 290Recurrence 278Squamous Cell Carcinoma of Head and Neck 246Stomach Neoplasms 229Pancreatic Neoplasms 228Leukemia, Myeloid, Acute 220Triple Negative Breast Neoplasms 190Endometrial Neoplasms 190Carcinoma, Renal Cell 182Lymphoma, Non-Hodgkin 179Carcinoma, Hepatocellular 177Small Cell Lung Carcinoma 165Leukemia, Lymphocytic, Chronic, B-Cell 156Advanced Solid Tumors 154Lymphoma, Follicular 148Urinary Bladder Neoplasms 139Lymphoma, Large B-Cell, Diffuse 138Lymphoma 137Advanced Solid Tumor 137Uterine Cervical Neoplasms 134Head and Neck Neoplasms 134

Interventions

Dexamethasone 2Cyclophosphamide 2Bortezomib 2venetoclax 1daratumumab 1belantamab mafodotin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
INDUSTRY × Amyloidosis × 1 year × Clear all
NCT05652335 2026-06-05

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

Janssen Research & Development, LLC

Phase 1 Recruiting
180 enrolled
Plasma cell

Amyloidosis, Multiple Myeloma, Recurrence

NCT07081646 2026-03-24

ALACRITY

Alexion Pharmaceuticals, Inc.

Phase 1/2 Recruiting
91 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT07224672 2026-03-17

ALANIS

GlaxoSmithKline

Phase 2 Not yet recruiting
60 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT03123029 2026-01-30

Expanded Access to Venetoclax

AbbVie

Available
LymphoidOther hematologic neoplasmPlasma cell

Amyloidosis, Leukemia, Plasma Cell, Lymphoma, Non-Hodgkin, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03201965 2025-11-26

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Janssen Research & Development, LLC

Phase 3 Completed
416 enrolled 28 charts 2 FDA
Plasma cell

Amyloidosis

NCT06097832 2025-07-10

NEXICART-2

Nexcella Inc.

Phase 1/2 Recruiting
40 enrolled
Plasma cell

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

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