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Phase

Phase 3 1Phase 2 1Phase 1/2 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Plasma cell 3

Conditions

Breast Neoplasms 158Lymphoma 156Precursor Cell Lymphoblastic Leukemia-Lymphoma 130Lymphoma, Non-Hodgkin 120Leukemia 119Leukemia, Lymphocytic, Chronic, B-Cell 116Multiple Myeloma 115Lymphoma, Large B-Cell, Diffuse 100Leukemia, Myeloid, Acute 97Hodgkin Disease 82Myelodysplastic Syndromes 78Lymphoma, Follicular 74Lymphoma, Mantle-Cell 72Burkitt Lymphoma 66Lymphoma, B-Cell, Marginal Zone 52Melanoma 49Leukemia, Myelogenous, Chronic, BCR-ABL Positive 48Neoplasms 45Recurrence 38Hematologic Neoplasms 34Lymphoma, Large-Cell, Immunoblastic 33Myeloproliferative Disorders 31Congenital Abnormalities 31Waldenstrom Macroglobulinemia 30Neoplasms, Plasma Cell 30Leukemia, Myelomonocytic, Chronic 30Lymphoma, B-Cell 29Primary Myelofibrosis 27Lymphoma, Large-Cell, Anaplastic 27Leukemia, Myeloid, Accelerated Phase 26

Interventions

Dexamethasone 9Calcium Dobesilate 7Bortezomib 5Melphalan 4Cyclophosphamide 3ixazomib 2Thalidomide 2Doxycycline 2dexamethasone acetate 1dexamethasone 21-phosphate 1daratumumab 1carfilzomib 1birtamimab 1auricularum 1Tacrolimus 1Lenalidomide 1Etoposide 1Doxorubicin 1Cisplatin 1Bendamustine Hydrochloride 1Antilymphocyte Serum 1ARQ 197 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × Amyloidosis × Cyclophosphamide × Clear all
NCT03201965 2025-11-26

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Janssen Research & Development, LLC

Phase 3 Completed
416 enrolled 28 charts 2 FDA
Plasma cell

Amyloidosis

NCT01864018 2025-07-24

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

Mayo Clinic

Phase 1/2 Completed
87 enrolled 13 charts
Plasma cell

Amyloidosis, Multiple Myeloma

NCT01548573 2017-06-14

Tandem Auto Transplantation in Myeloma Patients With <12 Months of Prior Treatment

University of Iowa

Phase 2 Terminated
19 enrolled 7 charts
Plasma cell

Amyloidosis, Endocrine System Diseases, Multiple Myeloma, Paraproteinemias, Polyneuropathies

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