Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 44Leukemia, Lymphocytic, Chronic, B-Cell 16Myelodysplastic Syndromes 7Leukemia, Biphenotypic, Acute 5Burkitt Lymphoma 5Waldenstrom Macroglobulinemia 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 3Myeloproliferative Disorders 3Lymphoma, Non-Hodgkin 3Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Recurrence 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Multiple Myeloma 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Hematologic Neoplasms 2Blast Crisis 2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Myelodysplastic-Myeloproliferative Diseases 1Lymphoma, B-Cell 1Leukemia, Myeloid, Accelerated Phase 1Leukemia, Myeloid 1Leukemia, Hairy Cell 1Leukemia 1Immunoglobulin Light-chain Amyloidosis 1Anemia, Refractory, with Excess of Blasts 1

Interventions

Cyclophosphamide 4fludarabine phosphate 3Whole-Body Irradiation 3Biopsy 3fludarabine 2Specimen Handling 2Melphalan 2Busulfan 2Antilymphocyte Serum 2venetoclax 1pegylated granulocyte colony-stimulating factor 1ivosidenib 1decitabine and cedazuridine drug combination 1Tacrolimus 1TAK-243 1Rituximab 1Peripheral Blood Stem Cell Transplantation 1Mycophenolic Acid 1Cytarabine 1Cyclosporine 1Cord Blood Stem Cell Transplantation 1Clofarabine 1CT-P10 1Bone Marrow Transplantation 111-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Anemia, Refractory, with Excess of Blasts × venetoclax × 30 days × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

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