Announcements Trials
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Phase

Phase 2/3 1Phase 2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 2

Conditions

Leukemia, Myeloid, Acute 111Leukemia, Lymphocytic, Chronic, B-Cell 31Myelodysplastic Syndromes 25Leukemia, Biphenotypic, Acute 11Leukemia 11Recurrence 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Leukemia, Myelomonocytic, Chronic 8Burkitt Lymphoma 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma, Mantle-Cell 7Lymphoma 7Hematologic Neoplasms 7Neoplasms 6Lymphoma, Large B-Cell, Diffuse 6Myeloproliferative Disorders 5Lymphoma, Non-Hodgkin 5Waldenstrom Macroglobulinemia 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Multiple Myeloma 3Lymphoma, Follicular 3Leukemia, Myeloid 3Sarcoma, Myeloid 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, B-Cell 2Immunoglobulin Light-chain Amyloidosis 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Blast Crisis 2Anemia, Refractory, with Excess of Blasts 2

Interventions

fludarabine phosphate 5Cyclophosphamide 5fludarabine 4Busulfan 4Whole-Body Irradiation 3Melphalan 3Biopsy 3Azacitidine 3venetoclax 2Vorinostat 2Specimen Handling 2Rituximab 2Mycophenolic Acid 2Cytarabine 2Clofarabine 2Antilymphocyte Serum 2thymoglobulin 1pegylated granulocyte colony-stimulating factor 1ivosidenib 1decitabine and cedazuridine drug combination 1cedazuridine 1Tacrolimus 1TAK-243 1Stem Cell Transplantation 1Peripheral Blood Stem Cell Transplantation 1Levetiracetam 1Lenalidomide 1Injections 1Idarubicin 1Granulocyte Colony-Stimulating Factor 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Anemia, Refractory, with Excess of Blasts × venetoclax × 90 days × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

NCT04256317 2026-04-30

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Taiho Oncology, Inc.

Phase 2/3 Recruiting
316 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

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