Announcements Trials
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Phase

Phase 3 1Phase 1 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 2

Conditions

Leukemia, Myeloid, Acute 17Leukemia, Promyelocytic, Acute 10Leukemia 9Myelodysplastic Syndromes 8Melanoma 5Congenital Abnormalities 4Myeloproliferative Disorders 3Myelodysplastic-Myeloproliferative Diseases 3Multiple Myeloma 3Leukemia, Myelomonocytic, Acute 3Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 3Leukemia, Monocytic, Acute 3Leukemia, Megakaryoblastic, Acute 3Leukemia, Erythroblastic, Acute 3Uterine Cervical Neoplasms 2Parkinson Disease 4, Autosomal Dominant Lewy Body 2Neuroblastoma 2Lymphoma, T-Cell, Cutaneous 2Leukemia, Myelomonocytic, Chronic 2Anemia, Refractory, with Excess of Blasts 2Wilms Tumor 1Uterine Cervical Dysplasia 1Small Cell Lung Carcinoma 1Skin Neoplasms 1Prostatic Neoplasms 1Precancerous Conditions 1Neoplasm Metastasis 1Lymphoma 1Lung Neoplasms 1Kidney Neoplasms 1

Interventions

fludarabine phosphate 42Cyclophosphamide 37Busulfan 31Cyclosporine 30Peripheral Blood Stem Cell Transplantation 29Cytarabine 27Mycophenolic Acid 25Antilymphocyte Serum 23Filgrastim 22Methotrexate 20Whole-Body Irradiation 18Radiotherapy 17Tacrolimus 16Methylprednisolone 13Etoposide 12Cord Blood Stem Cell Transplantation 12Melphalan 11Daunorubicin 10sargramostim 8fludarabine 8Idarubicin 8Granulocyte Colony-Stimulating Factor 8Thiotepa 6Cyclosporins 6tipifarnib 5merphos 5Topotecan 5Mitoxantrone 5Gemtuzumab 5Azacitidine 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Anemia, Refractory, with Excess of Blasts × Tretinoin × Clear all
NCT00006239 2017-09-29

Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT00005823 2013-12-18

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 3 Completed
2,000 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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