Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 8Myelodysplastic Syndromes 5Myeloproliferative Disorders 3Leukemia, Myelomonocytic, Chronic 3Myelodysplastic-Myeloproliferative Diseases 2Thrombocythemia, Essential 1Primary Myelofibrosis 1Polycythemia Vera 1Neurofibrosarcoma 1Neoplasms 1Mesothelioma, Malignant 1Mesothelioma 1Leukemia, Myeloid, Chronic-Phase 1Leukemia, Biphenotypic, Acute 1Anemia, Refractory, with Excess of Blasts 1Allogeneic Stem Cell Transplantation 1Accelerated Phase Myeloproliferative Neoplasm 1

Interventions

Cyclophosphamide 34Busulfan 32fludarabine phosphate 29Cyclosporine 24Mycophenolic Acid 22Peripheral Blood Stem Cell Transplantation 21Whole-Body Irradiation 19Antilymphocyte Serum 19Tacrolimus 15Methotrexate 15Cytarabine 15fludarabine 14Melphalan 14Cord Blood Stem Cell Transplantation 14Radiotherapy 13Filgrastim 12Methylprednisolone 9Granulocyte Colony-Stimulating Factor 9Etoposide 7Thiotepa 6thymoglobulin 5sargramostim 5Idarubicin 5Cyclosporins 5Clofarabine 5Azacitidine 5merphos 4Gemtuzumab 4Decitabine 4Arsenic Trioxide 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Anemia, Refractory, with Excess of Blasts × decitabine and cedazuridine drug combination × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

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