Announcements Trials
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Phase

Phase 1/2 1

Status

Withdrawn 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 12Myelodysplastic Syndromes 5Leukemia, Myelomonocytic, Chronic 3Leukemia, Biphenotypic, Acute 2Triple Negative Breast Neoplasms 1Systemic Mastocytosis With an Associated Hematologic Neoplasm 1Squamous Cell Carcinoma of Head and Neck 1Prostatic Neoplasms 1Neurofibrosarcoma 1Neuroendocrine Tumors 1Neoplasms 1Myeloproliferative Disorders 1Melanoma 1Leukemia, Myeloid, Chronic-Phase 1Cytopenia 1Central Nervous System Neoplasms 1Carcinoma, Squamous Cell 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Merkel Cell 1Breast Neoplasms 1BRCA1 Mutation 1Anemia, Refractory, with Excess of Blasts 1Allogeneic Stem Cell Transplantation 1Accelerated Phase Myeloproliferative Neoplasm 1

Interventions

fludarabine phosphate 50Cyclophosphamide 50Mycophenolic Acid 36Cyclosporine 33Busulfan 33Whole-Body Irradiation 32Peripheral Blood Stem Cell Transplantation 31Antilymphocyte Serum 24fludarabine 21Cord Blood Stem Cell Transplantation 21Tacrolimus 20Cytarabine 19Filgrastim 18Melphalan 17Radiotherapy 15Methylprednisolone 13Methotrexate 13Thiotepa 10Granulocyte Colony-Stimulating Factor 10Etoposide 9Cyclosporins 7Azacitidine 7thymoglobulin 5sargramostim 5Idarubicin 5Clofarabine 5Arsenic Trioxide 5Transplantation 4Sirolimus 4Gemtuzumab 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Anemia, Refractory, with Excess of Blasts × decitabine and cedazuridine drug combination × Clear all
NCT06284460 2026-02-13

Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms

M.D. Anderson Cancer Center

Phase 1/2 Withdrawn
Classical hematologyMyeloid

Anemia, Refractory, with Excess of Blasts, Myeloproliferative Disorders

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