Announcements Trials
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Phase

Phase 2 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 35Leukemia, Lymphocytic, Chronic, B-Cell 26Myelodysplastic Syndromes 11Lymphoma, Mantle-Cell 8Leukemia, Myelomonocytic, Chronic 8Neoplasms 7Burkitt Lymphoma 7Recurrence 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Multiple Myeloma 5Lymphoma, Non-Hodgkin 5Lymphoma, Follicular 5Lymphoma, B-Cell, Marginal Zone 5Lymphoma, B-Cell 5Myeloproliferative Disorders 4Lymphoma, Large B-Cell, Diffuse 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Leukemia, Biphenotypic, Acute 4Leukemia, B-Cell 4Waldenstrom Macroglobulinemia 3Leukemia 3Primary Myelofibrosis 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Lymphoma 2Hematologic Neoplasms 2Hematologic Diseases 2Thrombocytosis 1Thrombocythemia, Essential 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1

Interventions

Whole-Body Irradiation 4Cyclophosphamide 4fludarabine 3Tacrolimus 3Mycophenolic Acid 3Vorinostat 2Melphalan 2Granulocyte Colony-Stimulating Factor 2Busulfan 2Azacitidine 2venetoclax 1fludarabine phosphate 1decitabine and cedazuridine drug combination 1Triamcinolone 1Thiotepa 1Specimen Handling 1Sirolimus 1Peripheral Blood Stem Cell Transplantation 1Methotrexate 1Lenalidomide 1Etoposide 1Cyclosporine 1Cord Blood Stem Cell Transplantation 1Biopsy 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Active not recruiting × Anemia, Refractory, with Excess of Blasts × venetoclax × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

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