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Phase

Phase 3 1Phase 2 1Phase 1/2 1Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 62Myelodysplastic Syndromes 27Leukemia 13Leukemia, Myelomonocytic, Chronic 12Congenital Abnormalities 9Recurrence 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Myeloproliferative Disorders 8Primary Myelofibrosis 6Thrombocythemia, Essential 4Polycythemia Vera 4Neoplasms 4Melanoma 4Leukemia, Lymphocytic, Chronic, B-Cell 4Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 3Head and Neck Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Burkitt Lymphoma 3Blast Crisis 3Squamous Cell Carcinoma of Head and Neck 2Small Cell Lung Carcinoma 2Sarcoma 2Neuroblastoma 2Neoplasm Metastasis 2Myelodysplastic-Myeloproliferative Diseases 2Mesothelioma, Malignant 2Lymphoma, Non-Hodgkin 2Lymphoma, Large-Cell, Immunoblastic 2

Interventions

fludarabine phosphate 3sargramostim 2Whole-Body Irradiation 2Mycophenolic Acid 2Cyclosporine 2Cyclophosphamide 2Azacitidine 24-phenylbutyric acid 2tipifarnib 1poly ICLC 1bryostatin 1 1aldesleukin 1Tretinoin 1Thiotepa 1Tetradecanoylphorbol Acetate 1Nivolumab 1Methylprednisolone 1Lenalidomide 1Injections 1Immunologic Techniques 1Granulocyte-Macrophage Colony-Stimulating Factor 1Decitabine 1Cord Blood Stem Cell Transplantation 1Bryostatins 1Biopsy 1Arsenic Trioxide 1Antilymphocyte Serum 14'-thio-arabinofuranosylcytosine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Anemia, Refractory × Decitabine × Clear all
NCT03358719 2026-02-27

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Roswell Park Cancer Institute

Phase 1 Completed
8 enrolled 9 charts
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

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