Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Completed 3Unknown 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 3Classical hematology 3

Conditions

Leukemia, Myeloid, Acute 79Myelodysplastic Syndromes 42Leukemia 23Leukemia, Myelomonocytic, Chronic 20Congenital Abnormalities 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Recurrence 7Neoplasms 7Myeloproliferative Disorders 7Blast Crisis 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6Leukemia, Myeloid, Accelerated Phase 5Carcinoma, Non-Small-Cell Lung 5Thrombocythemia, Essential 4Primary Myelofibrosis 4Polycythemia Vera 4Leukemia, Lymphocytic, Chronic, B-Cell 4Myelodysplastic-Myeloproliferative Diseases 3Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Lung Neoplasms 3Leukemia, Myelomonocytic, Acute 3Leukemia, Monocytic, Acute 3Burkitt Lymphoma 3Anemia, Refractory, with Excess of Blasts 3Anemia, Refractory 3Small Cell Lung Carcinoma 2Neuroblastoma 2Neoplasm Metastasis 2Mesothelioma, Malignant 2

Interventions

Cyclophosphamide 23fludarabine phosphate 20Cyclosporine 19Busulfan 17Peripheral Blood Stem Cell Transplantation 14Mycophenolic Acid 14Antilymphocyte Serum 13Whole-Body Irradiation 12Radiotherapy 11Cord Blood Stem Cell Transplantation 10Methotrexate 9Filgrastim 9Methylprednisolone 8Cytarabine 6sargramostim 5Tacrolimus 5Melphalan 5Etoposide 5Cyclosporins 4merphos 3fludarabine 3Transplantation 3Thiotepa 3Granulocyte Colony-Stimulating Factor 3Decitabine 3bryostatin 1 2aldesleukin 2Topotecan 2Thioguanine 2Thalidomide 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Anemia, Refractory × Decitabine × Clear all
NCT03358719 2026-02-27

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Roswell Park Cancer Institute

Phase 1 Completed
8 enrolled 9 charts
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT01165996 2019-03-04

Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome

Case Comprehensive Cancer Center

Phase 1/2 Completed
25 enrolled 13 charts
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Thrombocytopenia, Leukemia, Myelomonocytic, Chronic

NCT00003361 2013-06-26

Decitabine in Treating Patients With Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 2 Completed
75 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

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