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NCT06989437 2026-05-20

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Phase 2/3 Recruiting

Gastrointestinal

Anorexia, Cachexia, Fatigue, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT07112196 2026-05-20

VINCIT

Phase 2/3 Recruiting

Anorexia, Cachexia, Neoplasms, Weight Loss

NCT07565415 2026-05-04

Nanocrystalline Megestrol Acetate Versus Placebo for Anorexia in Patients With Unresectable Hepatocellular Carcinoma Receiving TACE Combined With Targeted and Immunotherapy

Phase 2 Not yet recruiting

Gastrointestinal

Anorexia, Cachexia, Carcinoma, Hepatocellular, Malnutrition

NCT03637816 2026-04-15

Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer

Phase 2/3 Active not recruiting

Anorexia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04939090 2026-04-13

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Phase 3 Active not recruiting

Other hematologic neoplasm

Anorexia, Hematologic Neoplasms

NCT00488072 2026-01-26

Effects of Mirtazapine on Appetite in Advanced Cancer Patients

Phase 2 Active not recruiting

Anorexia, Sleep Initiation and Maintenance Disorders, Weight Loss

NCT05705492 2026-01-21

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

Phase 2 Recruiting

Gastrointestinal

Anorexia, Cachexia, Esophageal Neoplasms, Neoplasms, Colorectal Neoplasms, Weight Loss

NCT04844970 2025-11-17

Anamorelin Study for Advanced Pancreatic Cancer

Phase 2 Terminated

4 enrolled 12 charts

Gastrointestinal

Anorexia, Cachexia, Pancreatic Neoplasms, Weight Loss

NCT00489307 2025-11-12

Dexamethasone for Symptom Burden in Advanced Cancer Patients

Phase 2 Active not recruiting

132 enrolled 15 charts

Anorexia, Fatigue, Nausea, Pain

NCT07179094 2025-09-17

The Effect of a Protective Oral Care Protocol Using Peppermint Oil Mouthwash

Phase NA Not yet recruiting

Other hematologic neoplasm

Anorexia, Nausea, Vomiting, Hematologic Neoplasms

NCT04906746 2025-07-28

Ruxolitinib for Cancer Cachexia

Phase EARLY_PHASE1 Active not recruiting

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Muscular Atrophy

NCT05546476 2025-05-31

PROACC-1

Phase 2 Completed

187 enrolled 24 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT05243251 2024-10-03

Olanzapine Anorexia Cachexia

Phase 3 Completed

Anorexia

NCT06517199 2024-07-24

Olanzapine for Cancer Related Anorexia-cachexia Syndrome

Phase 3 Recruiting

Anorexia, Cachexia

NCT02887586 2024-01-30

The Effectiveness and Mechanism Study of Auricular Needling in Treating Cancer Induced Anorexia

Phase NA Completed

60 enrolled 12 charts

Anorexia, Anorexia Nervosa, Neoplasms

NCT04803305 2024-01-12

Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia

Phase 1 Completed

18 enrolled 14 charts

BreastGastrointestinalGenitourinaryGynecologicThoracic

Anorexia, Breast Neoplasms, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT03245658 2023-12-18

The Effect of Cannabis in Pancreatic Cancer

Phase 2 Withdrawn

Gastrointestinal

Anorexia, Cachexia, Marijuana Abuse, Neoplasms, Pancreatic Neoplasms

NCT04299048 2023-12-14

Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.

Phase 1 Completed

11 enrolled 13 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Muscular Atrophy, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT03283488 2023-07-07

Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.

Phase 2 Completed

Anorexia, Cachexia, Neoplasms

NCT04748523 2023-04-27

Effect of Mirtazapine Versus Placebo in Patients With Non-small Cell Lung Cancer and Anorexia

Phase NA Completed

Anorexia, Carcinoma, Non-Small-Cell Lung

NCT04430842 2023-01-18

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Phase 1 Completed

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Sleepiness, Mesothelioma, Malignant, Anorexia, Astrocytoma, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Headache, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Seizures, Speech Disorders, Stomach Neoplasms, Thymoma, Tongue Neoplasms, Urologic Neoplasms, Vomiting, Colorectal Neoplasms, Cholangiocarcinoma

NCT02830620 2022-10-26

CHIMIOKINES

Phase NA Completed

Gastrointestinal

Anorexia, Pancreatic Neoplasms

NCT05380479 2022-05-18

Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.

Phase 2 Unknown

Anorexia, Cachexia, Neoplasms

NCT00006799 2021-09-09

Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Anorexia, Cachexia, Head and Neck Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00031785 2021-09-09

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Phase 3 Completed

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00081250 2020-04-29

Creatine in Treating Patients With Cancer-Associated Weight Loss

Phase 3 Completed

Anorexia, Body Weight Changes, Cachexia

NCT01503346 2020-02-17

TCM

Phase 2 Completed

Anorexia

NCT01317550 2020-02-10

A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil

Phase NA Completed

14 enrolled 10 charts

cyclopia sequence, Sleepiness, Anorexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Lung Neoplasms, Pain, Parasomnias

NCT02445378 2019-04-05

Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing Chemotherapy

Phase NA Completed

Anorexia, Anxiety Disorders, Depression, Dyspnea, Sleep Initiation and Maintenance Disorders, Nausea, Pain

NCT02148159 2019-01-17

Acupuncture for Unintentional Weight Loss and Anorexia With GI Cancer

Phase NA Completed

Gastrointestinal

Anorexia, Cachexia, Gastrointestinal Neoplasms, Neoplasms

NCT01941810 2018-07-03

Bovine Lactoferrin Supplement in Improving Taste in Patients With Cancer Receiving Chemotherapy

Phase NA Completed

Anorexia, Cachexia, Neoplasms

NCT00040885 2016-12-07

Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)

Phase 3 Completed

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Lung Neoplasms

NCT02802540 2016-08-31

Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients

Phase 2/3 Unknown

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung

NCT00031707 2016-07-14

Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite

Phase 3 Completed

Anorexia, Cachexia

NCT00637728 2016-06-23

Treatment of Cancer-anorexia Using Megestrol Acetate Concentrated Suspension in Lung or Pancreatic Cancer Patients

Phase 3 Terminated

5 enrolled 8 charts

GastrointestinalThoracic

Anorexia, Body Weight, Cachexia, Lung Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT00558558 2016-05-13

Haelan and Nutrition in Cancer Patients

Phase 2 Terminated

6 enrolled 5 charts

Anorexia, Cachexia, Weight Loss

NCT00637806 2016-05-02

Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension

Phase 3 Terminated

4 enrolled 6 charts

Anorexia, Body Weight, Cachexia, Neoplasms, Weight Loss

NCT00425906 2016-01-12

Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer

Phase NA Withdrawn

Anorexia, Constipation, Intestinal Obstruction, Pain

NCT02619266 2015-12-04

The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers

Phase 2/3 Unknown

Anorexia

NCT01200602 2015-11-25

Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy

Phase 2 Terminated

Anorexia, Body Weight Changes

NCT01501396 2014-02-03

Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite

Phase 2 Withdrawn

Anorexia

NCT00219817 2013-09-02

Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss

Phase 2 Completed

Anorexia, Cachexia

NCT00379353 2013-02-04

The Effects of Thalidomide on Symptom Clusters

Phase 2 Completed

32 enrolled 14 charts

Anorexia, Fatigue

NCT00527319 2013-01-30

VT-122

Phase 2 Completed

37 enrolled 9 charts

Anorexia, Cachexia

NCT00513357 2012-12-11

Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients

Phase 3 Completed

82 enrolled 7 charts

GastrointestinalThoracic

Anorexia, Cachexia, Gastrointestinal Neoplasms, Lung Neoplasms, Weight Loss

NCT01206335 2012-11-27

Open Label Study With OHR/AVR118 in Advanced Cancer Patients With Anorexia-Cachexia

Phase 2 Unknown

Anorexia, Fatigue, Weight Loss

NCT00412425 2012-05-04

Palonosetron for Prevention of Biochemotherapy Induced Nausea and Vomiting

Phase 1/2 Completed

30 enrolled 4 charts

Anorexia, Melanoma, Nausea, Vomiting, Weight Loss

NCT01540019 2012-02-28

Paullinia Cupana for Anorexia in Oncologic Patients

Phase 1/2 Unknown

Anorexia, Weight Loss

NCT00060502 2011-05-17

A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia

Phase 2 Completed

Classical hematologyGastrointestinal

Anemia, Anorexia, Cachexia, Pancreatic Neoplasms

NCT00046904 2011-05-05

Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer

Phase 3 Completed

Anorexia, Cachexia