Announcements Trials
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Phase

Phase 3 2Phase 2 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 3

Conditions

Carcinoma, Non-Small-Cell Lung 211Lung Neoplasms 77Triple Negative Breast Neoplasms 67Breast Neoplasms 67Ovarian Neoplasms 53Squamous Cell Carcinoma of Head and Neck 49Small Cell Lung Carcinoma 47Fallopian Tube Neoplasms 34Endometrial Neoplasms 34Neoplasms 31Parkinson Disease 4, Autosomal Dominant Lewy Body 28Neoplasm Metastasis 28Head and Neck Neoplasms 24Prostatic Neoplasms 20Esophageal Neoplasms 18Carcinoma 18Urinary Bladder Neoplasms 16Colorectal Neoplasms 16Uterine Cervical Neoplasms 14Oropharyngeal Neoplasms 14Carcinoma, Transitional Cell 14Carcinoma, Squamous Cell 14Esophageal Squamous Cell Carcinoma 12Brain Neoplasms 12Stomach Neoplasms 10Pancreatic Neoplasms 10Lymphoma, Large B-Cell, Diffuse 10Mouth Neoplasms 9Laryngeal Neoplasms 9Advanced Solid Tumors 9

Interventions

pembrolizumab 7Nivolumab 7Specimen Handling 6Mitomycin 6Magnetic Resonance Spectroscopy 6Capecitabine 6Radiotherapy 5Fluorouracil 4Drug Therapy 4Biopsy 4Radiation 3Paclitaxel 3Ipilimumab 3Fluorodeoxyglucose F18 3Carboplatin 3dehydroftorafur 2atezolizumab 2aldesleukin 2Tomography, X-Ray Computed 2Sigmoidoscopy 2Radiotherapy, Intensity-Modulated 2Proctoscopy 2Mitozytrex 2Colonoscopy 2CTLA-4 Antigen 2Adoptive Transfer 2trastuzumab deruxtecan 1spartalizumab 1enzalutamide 1entinostat 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Anus Neoplasms × Carboplatin × 1 year × Clear all
NCT04444921 2026-05-29

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

National Cancer Institute (NCI)

Phase 3 Active not recruiting
205 enrolled
Gastrointestinal

Anal Canal Carcinoma, Anus Neoplasms

NCT06493019 2026-03-23

Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer

Hoosier Cancer Research Network

Phase 2 Recruiting
23 enrolled
Gastrointestinal

Anus Neoplasms

NCT04472429 2025-11-03

Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

Incyte Corporation

Phase 3 Completed
308 enrolled 17 charts 1 FDA
Gastrointestinal

Anus Neoplasms, Carcinoma, Squamous Cell

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