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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1Gynecologic 1Gastrointestinal 1

Conditions

Rectal Neoplasms 2Lymphoma, Non-Hodgkin 2Lymphoma 2Vulvar Neoplasms 1Vulvar Diseases 1Uterine Cervical Neoplasms 1Uterine Cervical Dysplasia 1Stomach Neoplasms 1Prostatic Neoplasms 1Papillomavirus Infections 1Pancreatic Neoplasms 1Oropharyngeal Neoplasms 1Myelodysplastic Syndromes 1Multiple Myeloma 1Leukemia 1Hodgkin Disease 1Hematologic Neoplasms 1Gastrointestinal Neoplasms 1Colonic Neoplasms 1Carcinoma in Situ 1Anus Neoplasms 1

Interventions

Cyclophosphamide 3fludarabine 2aldesleukin 2Fluorouracil 2spartalizumab 1niraparib 1fludarabine phosphate 1entinostat 1bintrafusp alfa protein, human 1Tomography, X-Ray Computed 1Therapeutics 1SRA737 1Papillomavirus Vaccines 1NHS-IL12 immunocytokine 1Mn(III) meso-tetrakis(N-n-butoxyethylpyridinium-2-yl)porphyrin 1Mitomycin 1Magnetic Resonance Imaging 1Leucovorin 1Interleukin-2 1Ibuprofen 1Epinephrine 1Electrocardiography 1Diphenhydramine 1Dexamethasone 1Calcium Dobesilate 1Biopsy 1Adoptive Transfer 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Anus Neoplasms × Magnetic Resonance Imaging × Clear all
NCT04432597 2026-05-18

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
39 enrolled
GastrointestinalGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Rectal Neoplasms

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