Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Not yet recruiting 1Enrolling by invitation 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Lymphoid 1

Conditions

Burkitt Lymphoma 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Lung Neoplasms 6Leukemia, Myeloid, Acute 6Breast Neoplasms 6Meningeal Carcinomatosis 5Carcinoma, Non-Small-Cell Lung 5Lymphoma, Large B-Cell, Diffuse 4Leukemia, Biphenotypic, Acute 4Myelodysplastic Syndromes 3Glioblastoma 3Astrocytoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2Lymphoma 2Glioma 2Brain Neoplasms 2Uveal Melanoma 1Rhabdomyosarcoma 1Oligodendroglioma 1Nevus 1Neoplastic Cells, Circulating 1Neoplasm Recurrence, Local 1Multiple Myeloma 1Meningioma 1Meningeal Neoplasms 1Melanoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, T-Cell 1

Interventions

Temozolomide 19Magnetic Resonance Spectroscopy 15Specimen Handling 13Radiotherapy 13Radiation 9Biopsy 5pembrolizumab 4Radiotherapy, Intensity-Modulated 4Nivolumab 4Bevacizumab 4vorasidenib 3trametinib 3Surgical Procedures, Operative 3Spinal Puncture 3tovorafenib 2dabrafenib 2Restraint, Physical 2Leukapheresis 2Ipilimumab 2Genetic Therapy 2Fluorodeoxyglucose F18 2Eflornithine 2Craniotomy 2Carboplatin 214-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene 2vocimagene amiretrorepvec 1veliparib 1trastuzumab deruxtecan 1tocilizumab 1ribociclib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Astrocytoma × Spinal Puncture × 1 year × Clear all
NCT03919071 2026-05-27

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
58 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Mayo Clinic

Phase 1/2 Not yet recruiting
33 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT06896110 2025-06-26

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

University of Iowa

Phase 1 Enrolling by invitation
34 enrolled
CNS

Astrocytoma, Glioblastoma

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