Announcements Trials
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Phase

Phase 2 2Phase 1/2 1Phase 1 1

Status

Recruiting 2Active not recruiting 2

Sponsor Class

NIH 2NETWORK 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Lymphoid 1

Conditions

Prostatic Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Glioblastoma 6Rectal Neoplasms 5Oropharyngeal Neoplasms 5Breast Neoplasms 5Squamous Cell Carcinoma of Head and Neck 4Lung Neoplasms 4Burkitt Lymphoma 4Astrocytoma 4Urinary Bladder Neoplasms 3Mouth Neoplasms 3Glioma 3Carcinoma, Squamous Cell 3Adenocarcinoma of Lung 3Rhabdomyosarcoma 2Pancreatic Neoplasms 2Mesothelioma, Malignant 2Lymphoma, Follicular 2Laryngeal Neoplasms 2Hodgkin Disease 2Esophageal Neoplasms 2Carcinoma 2Breast Carcinoma In Situ 2Adenocarcinoma, Bronchiolo-Alveolar 2Wilms Tumor 1Vaginal Neoplasms 1Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Skin Neoplasms 1

Interventions

Temozolomide 6Magnetic Resonance Spectroscopy 5Specimen Handling 4Radiotherapy 4Radiation 3trametinib 2dabrafenib 2Radiotherapy, Intensity-Modulated 2Bevacizumab 2vorasidenib 1veliparib 1trastuzumab deruxtecan 1ribociclib 1Spinal Puncture 1Protons 1Proton Therapy 1Pluvicto 1Nivolumab 1Magnetic Resonance Imaging 1Ipilimumab 1Flucytosine 1Everolimus 1Carboplatin 1CTLA-4 Antigen 1AZD1390 13-aminopyridine-2-carboxaldehyde thiosemicarbazone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Astrocytoma × Radiotherapy × 30 days × Clear all
NCT05765812 2026-05-28

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Debiopharm International SA

Phase 1/2 Recruiting
116 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT03581292 2026-05-27

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

National Cancer Institute (NCI)

Phase 2 Active not recruiting
38 enrolled 13 charts
CNS

Astrocytoma, Glioblastoma, Glioma

NCT03919071 2026-05-27

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
58 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

NCT06894979 2026-05-15

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Children's Oncology Group

Phase 1 Recruiting
54 enrolled
CNS

Astrocytoma

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