Announcements Trials
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Phase

Phase 1 3Phase NA 1Phase 2 1

Status

Terminated 3Unknown 1Completed 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Keratosis, Actinic 18Brain Neoplasms 18Glioblastoma 16Glioma 15Carcinoma, Basal Cell 7Astrocytoma 5Gliosarcoma 4Skin Neoplasms 3Precancerous Conditions 3Oligodendroglioma 3Mouth Neoplasms 3Carcinoma, Squamous Cell 3Squamous Intraepithelial Lesions 2Skull Base Neoplasms 2Sarcoma 2Pituitary Neoplasms 2Neoplasms 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Head and Neck Neoplasms 2Central Nervous System Neoplasms 2Basal Cell Nevus Syndrome 2Urinary Bladder Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sezary Syndrome 1Oropharyngeal Neoplasms 1Nonmelanoma Skin Cancers 1Non-Melanoma Skin Cancer (NMSC) 1Neurofibromatosis 1 1Neurofibromatoses 1

Interventions

Temozolomide 61Radiotherapy 25Bevacizumab 21Magnetic Resonance Spectroscopy 20Irinotecan 18Filgrastim 15Carboplatin 15Carmustine 11Surgical Procedures, Operative 10Etoposide 9antineoplaston AS 2-1 8antineoplaston A10 8Specimen Handling 8sargramostim 7Radiation 7Peripheral Blood Stem Cell Transplantation 7Everolimus 7Biopsy 7Vincristine 6Radiotherapy, Intensity-Modulated 6Procarbazine 6O(6)-benzylguanine 6Erlotinib Hydrochloride 6Topotecan 5Melphalan 5Magnetic Resonance Imaging 5Lomustine 5Genetic Therapy 5Cyclophosphamide 5Aminolevulinic Acid 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Astrocytoma × Aminolevulinic Acid × Clear all
NCT06665724 2026-02-27

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Universität Münster

Phase 1 Completed
16 enrolled
CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT01148966 2017-02-15

Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors

University of Washington

Phase 1 Terminated
6 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02119338 2017-01-06

5-ALA in Recurrent Glioma

St. Joseph's Hospital and Medical Center, Phoenix

Phase NA Unknown
60 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01502605 2017-01-05

Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Terminated
6 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioma

NCT01351519 2016-03-17

A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors

MultiCare Health System Research Institute

Phase 2 Terminated
16 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

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