Announcements Trials
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Phase

Phase 1 3Phase NA 1Phase 2 1

Status

Terminated 3Unknown 1Completed 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Keratosis, Actinic 33Glioblastoma 20Brain Neoplasms 19Glioma 15Carcinoma, Basal Cell 9Skin Neoplasms 5Precancerous Conditions 5Astrocytoma 5Gliosarcoma 4Oligodendroglioma 3Mouth Neoplasms 3Carcinoma, Squamous Cell 3Squamous Intraepithelial Lesions 2Skull Base Neoplasms 2Skin Diseases 2Sarcoma 2Neoplasms 2Mycosis Fungoides 2Meningioma 2Lymphoma, T-Cell, Cutaneous 2Leukoplakia, Oral 2Head and Neck Neoplasms 2Basal Cell Nevus Syndrome 2Urinary Bladder Neoplasms 1The Aim of the Study is to Evaluate the Efficacy of Photodynamic Therapy as an 1Squamous Cell Carcinoma of Head and Neck 1Sezary Syndrome 1Pituitary Neoplasms 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1

Interventions

Temozolomide 111Radiotherapy 60Carboplatin 30Bevacizumab 30Magnetic Resonance Spectroscopy 28Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 17Lomustine 16Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Astrocytoma × Aminolevulinic Acid × Clear all
NCT06665724 2026-02-27

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Universität Münster

Phase 1 Completed
16 enrolled
CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT01148966 2017-02-15

Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors

University of Washington

Phase 1 Terminated
6 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02119338 2017-01-06

5-ALA in Recurrent Glioma

St. Joseph's Hospital and Medical Center, Phoenix

Phase NA Unknown
60 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01502605 2017-01-05

Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Terminated
6 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioma

NCT01351519 2016-03-17

A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors

MultiCare Health System Research Institute

Phase 2 Terminated
16 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

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