Clinical Trials Browser

Phase 1 × Astrocytoma × Irinotecan × Clear all

NCT02192359 2025-11-14

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Phase 1 Active not recruiting

18 enrolled 16 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00138216 2023-10-02

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Phase 1 Completed

42 enrolled

CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00671801 2018-11-13

Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I

Phase 1 Terminated

24 enrolled

CNSSarcoma

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00006025 2018-06-27

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Phase 1 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01999270 2016-10-21

Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors

Phase 1 Completed

6 enrolled

CNS

Astrocytoma, Ganglioneuroma, Glioma, Ganglioglioma

NCT00003484 2015-04-23

Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors

Phase 1 Completed

21 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00005951 2014-08-22

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

Phase 1 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00611728 2014-07-21

Ph I SU011248 + Irinotecan in Treatment of Pts w MG

Phase 1 Completed

25 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT02055196 2014-06-02

Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Phase 1 Withdrawn

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT00101270 2013-06-05

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Phase 1 Completed

24 enrolled

CNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Colonic Neoplasms, Medulloblastoma, Melanoma, Nasopharyngeal Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Osteosarcoma, Lymphoma, Large B-Cell, Diffuse, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00003463 2013-02-18

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

Phase 1 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma