Announcements Trials
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Phase

Phase 3 2Phase 1 1

Status

Withdrawn 1Terminated 1Completed 1

Sponsor Class

OTHER 2NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 2

Conditions

Neuroblastoma 44Ganglioneuroblastoma 5Medulloblastoma 4Lung Neoplasms 4Leukemia, Myelomonocytic, Juvenile 4Glioblastoma 4Brain Neoplasms 4Uterine Cervical Neoplasms 3Small Cell Lung Carcinoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Leukemia, Myeloid, Acute 3Leukemia 3Kidney Neoplasms 3Head and Neck Neoplasms 3Gliosarcoma 3Glioma 3Central Nervous System Neoplasms 3Carcinoma, Renal Cell 3Carcinoma, Non-Small-Cell Lung 3Astrocytoma 3Squamous Cell Carcinoma of Head and Neck 2Rhabdoid Tumor 2Recurrence 2Prostatic Neoplasms 2Pinealoma 2Oligodendroglioma 2Neoplasms 2Myelodysplastic Syndromes 2Mycosis Fungoides 2Lymphoma, Large B-Cell, Diffuse 2

Interventions

Temozolomide 111Radiotherapy 60Carboplatin 30Bevacizumab 30Magnetic Resonance Spectroscopy 28Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 17Lomustine 16Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Astrocytoma × Isotretinoin × Clear all
NCT01103375 2018-08-01

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

Wake Forest University Health Sciences

Phase 1 Terminated
5 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00078988 2015-05-07

High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas

Children's Oncology Group

Phase 3 Completed
1 enrolled
CNS

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms

NCT00003564 2012-02-22

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

M.D. Anderson Cancer Center

Phase 3 Withdrawn
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

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