Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Breast Neoplasms 12Brain Neoplasms 6Breast Neoplasms, Male 5Glioblastoma 4Gliosarcoma 3Stomach Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Salivary Gland Neoplasms 2Prostatic Neoplasms 2Oligodendroglioma 2Glioma 2Gallbladder Neoplasms 2Ependymoma 2Carcinoma, Hepatocellular 2Bile Duct Neoplasms 2Astrocytoma 2Tongue Neoplasms 1Thyroid Neoplasms 1Thymoma 1Spinal Cord Neoplasms 1Small Cell Lung Carcinoma 1Skin Neoplasms 1Neoplasms 1Melanoma 1Medulloblastoma 1Insulin-Like Growth Factor I, Resistance To 1Familial ependymoma 1Esophageal Neoplasms 1Endometrial Neoplasms 1Central Nervous System Neoplasms 1

Interventions

Temozolomide 22Radiotherapy 17Carmustine 9Magnetic Resonance Spectroscopy 8Carboplatin 8Vorinostat 6Surgical Procedures, Operative 6Radiation 6Cisplatin 6Chemotherapy, Adjuvant 6O(6)-benzylguanine 5Erlotinib Hydrochloride 5Cyclophosphamide 5Bevacizumab 5veliparib 4Vincristine 4Thiotepa 4Specimen Handling 4Radiotherapy, Intensity-Modulated 4Peripheral Blood Stem Cell Transplantation 4Methotrexate 4Lenalidomide 4Filgrastim 42,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 4Radiotherapy, Conformal 3Procarbazine 3Lomustine 3Iodine-125 3Immunoglobulin G 3Etoposide 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Astrocytoma × Lapatinib × Clear all
NCT02101905 2024-11-06

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

National Cancer Institute (NCI)

Phase 1 Completed
29 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00095940 2014-05-23

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

National Cancer Institute (NCI)

Phase 1/2 Completed
52 enrolled 17 charts
CNS

Familial ependymoma, Astrocytoma, Glioblastoma, Medulloblastoma, Oligodendroglioma

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