Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Breast Neoplasms 111Neoplasms 22Neoplasm Metastasis 17Brain Neoplasms 15Breast Neoplasms, Male 13Head and Neck Neoplasms 7Squamous Cell Carcinoma of Head and Neck 6Stomach Neoplasms 5Glioblastoma 5Colorectal Neoplasms 5Prostatic Neoplasms 4Ovarian Neoplasms 4Inflammatory Breast Neoplasms 4Carcinoma, Ovarian Epithelial 4Salivary Gland Neoplasms 3Lung Neoplasms 3Gliosarcoma 3Glioma 3Ependymoma 3Carcinoma, Non-Small-Cell Lung 3Urinary Bladder Neoplasms 2Unspecified Adult Solid Tumor, Protocol Specific 2Solid Tumors 2Recurrence 2Osteitis Deformans 2Oligodendroglioma 2Neuroma, Acoustic 2Neurofibromatosis 2 2Gallbladder Neoplasms 2Esophageal Neoplasms 2

Interventions

Temozolomide 66Radiotherapy 34Carboplatin 22Carmustine 21Bevacizumab 21Irinotecan 18Filgrastim 18Surgical Procedures, Operative 14Vincristine 11Peripheral Blood Stem Cell Transplantation 11Etoposide 11Radiation 10O(6)-benzylguanine 10Magnetic Resonance Spectroscopy 9Lomustine 9Procarbazine 8Erlotinib Hydrochloride 8sargramostim 7IL13-PE38 7Everolimus 7Cyclophosphamide 7Chemotherapy, Adjuvant 7Thiotepa 6Radiotherapy, Intensity-Modulated 6Imatinib Mesylate 6Granulocyte Colony-Stimulating Factor 6Drug Therapy 6Cisplatin 6temsirolimus 5antineoplaston AS 2-1 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Astrocytoma × Lapatinib × Clear all
NCT02101905 2024-11-06

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

National Cancer Institute (NCI)

Phase 1 Completed
29 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00095940 2014-05-23

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

National Cancer Institute (NCI)

Phase 1/2 Completed
52 enrolled 17 charts
CNS

Familial ependymoma, Astrocytoma, Glioblastoma, Medulloblastoma, Oligodendroglioma

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