Announcements Trials
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Phase

Phase 1 4Phase 2 1

Status

Completed 3Terminated 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 2

Conditions

Multiple Myeloma 70Leukemia, Lymphocytic, Chronic, B-Cell 26Lymphoma, Mantle-Cell 15Lymphoma, Follicular 15Lymphoma, Large B-Cell, Diffuse 14Leukemia, Myeloid, Acute 14Lymphoma, B-Cell, Marginal Zone 13Lymphoma, Non-Hodgkin 12Recurrence 11Neoplasms, Plasma Cell 10Lymphoma 10Myelodysplastic Syndromes 9Hodgkin Disease 8Neoplasms 7Leukemia 7Burkitt Lymphoma 7Waldenstrom Macroglobulinemia 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, T-Cell, Cutaneous 6Lymphoma, B-Cell 6Sezary Syndrome 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Mycosis Fungoides 4Lymphoma, T-Cell, Peripheral 4Lymphoma, Large-Cell, Immunoblastic 4Astrocytoma 4Smoldering Multiple Myeloma 3Prostatic Neoplasms 3Oligodendroglioma 3Melanoma 3

Interventions

Temozolomide 38Radiotherapy 17Filgrastim 14Surgical Procedures, Operative 11Irinotecan 11Carmustine 10Carboplatin 10Radiation 9O(6)-benzylguanine 9Magnetic Resonance Spectroscopy 9Specimen Handling 7Granulocyte Colony-Stimulating Factor 7Flucytosine 7sargramostim 6Radiotherapy, Intensity-Modulated 5Peripheral Blood Stem Cell Transplantation 5Etoposide 5Erlotinib Hydrochloride 5Bevacizumab 5vocimagene amiretrorepvec 4Vorinostat 4Thiotepa 4Melphalan 4Lenalidomide 4IL13-PE38 4Genetic Therapy 4Cyclophosphamide 4Chemotherapy, Adjuvant 4Busulfan 4lonafarnib 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Astrocytoma × Lenalidomide × Clear all
NCT01222754 2022-01-03

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
29 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioma

NCT00671801 2018-11-13

Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I

M.D. Anderson Cancer Center

Phase 1 Terminated
24 enrolled
CNSSarcoma

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00036894 2015-04-30

CC-5013 in Treating Patients With Recurrent Glioma

National Cancer Institute (NCI)

Phase 1 Completed
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00100880 2013-09-30

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
45 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

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