Announcements Trials
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Phase

Phase 1 3

Status

Recruiting 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Lymphoid 1

Conditions

Lymphoma, Large B-Cell, Diffuse 15Multiple Myeloma 14Lymphoma, Non-Hodgkin 12Leukemia, Myeloid, Acute 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Leukemia, Lymphocytic, Chronic, B-Cell 9Lymphoma, Mantle-Cell 8Lymphoma, Follicular 8Lymphoma, B-Cell 7Lymphoma 7Glioblastoma 7Hodgkin Disease 6Burkitt Lymphoma 6Prostatic Neoplasms 5Recurrence 4Lymphoma, B-Cell, Marginal Zone 4Leukemia 4Hematologic Neoplasms 4Breast Neoplasms 4Waldenstrom Macroglobulinemia 3Triple Negative Breast Neoplasms 3Sarcoma 3Ovarian Neoplasms 3Myelodysplastic Syndromes 3Melanoma 3Lymphoma, Large-Cell, Anaplastic 3Glioma 3Astrocytoma 3Sezary Syndrome 2Sarcoma, Synovial 2

Interventions

Temozolomide 115Radiotherapy 63Magnetic Resonance Spectroscopy 30Carboplatin 30Bevacizumab 30Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 18Lomustine 17Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Astrocytoma × Leukapheresis × Clear all
NCT07544992 2026-05-06

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

City of Hope Medical Center

Phase 1 Recruiting
24 enrolled
CNS

Astrocytoma, Glioblastoma

NCT06815029 2025-06-26

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

City of Hope Medical Center

Phase 1 Recruiting
27 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT01808820 2022-07-20

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

University of Miami

Phase 1 Completed
20 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

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