Announcements Trials
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Phase

Phase 1 3

Status

Recruiting 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Lymphoid 1

Conditions

Lymphoma, Large B-Cell, Diffuse 14Multiple Myeloma 12Leukemia, Myeloid, Acute 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma, Non-Hodgkin 8Lymphoma, Mantle-Cell 8Lymphoma, Follicular 8Leukemia, Lymphocytic, Chronic, B-Cell 8Glioblastoma 7Lymphoma, B-Cell 6Burkitt Lymphoma 6Prostatic Neoplasms 5Recurrence 4Lymphoma, B-Cell, Marginal Zone 4Lymphoma 4Hematologic Neoplasms 4Breast Neoplasms 4Triple Negative Breast Neoplasms 3Sarcoma 3Ovarian Neoplasms 3Melanoma 3Hodgkin Disease 3Glioma 3Astrocytoma 3Waldenstrom Macroglobulinemia 2Sezary Syndrome 2Sarcoma, Synovial 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Myelodysplastic Syndromes 2Mycosis Fungoides 2

Interventions

Temozolomide 61Radiotherapy 25Bevacizumab 21Magnetic Resonance Spectroscopy 20Irinotecan 18Filgrastim 15Carboplatin 15Carmustine 11Surgical Procedures, Operative 10Etoposide 9antineoplaston AS 2-1 8antineoplaston A10 8Specimen Handling 8sargramostim 7Radiation 7Peripheral Blood Stem Cell Transplantation 7Everolimus 7Biopsy 7Vincristine 6Radiotherapy, Intensity-Modulated 6Procarbazine 6O(6)-benzylguanine 6Erlotinib Hydrochloride 6Topotecan 5Melphalan 5Magnetic Resonance Imaging 5Lomustine 5Genetic Therapy 5Cyclophosphamide 5Aminolevulinic Acid 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Astrocytoma × Leukapheresis × Clear all
NCT07544992 2026-06-12

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

City of Hope Medical Center

Phase 1 Recruiting
24 enrolled
CNS

Astrocytoma, Glioblastoma

NCT06815029 2025-06-26

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

City of Hope Medical Center

Phase 1 Recruiting
27 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT01808820 2022-07-20

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

University of Miami

Phase 1 Completed
20 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

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