Announcements Trials
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Phase

Phase 1/2 2Phase 1 2

Status

Completed 3Suspended 1

Sponsor Class

OTHER 6NIH 4NETWORK 2

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 3Lymphoid 1

Conditions

Squamous Cell Carcinoma of Head and Neck 10Gliosarcoma 7Glioblastoma 7Rectal Neoplasms 4Oropharyngeal Neoplasms 4Astrocytoma 4Head and Neck Neoplasms 3Uterine Cervical Neoplasms 2Salivary Gland Neoplasms 2Neoplasm Metastasis 2Mouth Neoplasms 2Laryngeal Neoplasms 2Hypopharyngeal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Carcinoma 2Vaginal Neoplasms 1Thyroid Carcinoma, Anaplastic 1Stomach Neoplasms 1Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 1Sarcoma 1Radiation Injuries 1Prostatic Neoplasms 1Pinealoma 1Pancreatic Neoplasms 1Pancreatic Intraductal Neoplasms 1Ovarian Neoplasms 1Ototoxicity 1Osteosarcoma 1Oligodendroglioma 1Neuroma, Acoustic 1

Interventions

Temozolomide 22Radiotherapy 17Carmustine 9Magnetic Resonance Spectroscopy 8Carboplatin 8Vorinostat 6Surgical Procedures, Operative 6Radiation 6Cisplatin 6Chemotherapy, Adjuvant 6O(6)-benzylguanine 5Erlotinib Hydrochloride 5Cyclophosphamide 5Bevacizumab 5veliparib 4Vincristine 4Thiotepa 4Specimen Handling 4Radiotherapy, Intensity-Modulated 4Peripheral Blood Stem Cell Transplantation 4Methotrexate 4Lenalidomide 4Filgrastim 42,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 4Radiotherapy, Conformal 3Procarbazine 3Lomustine 3Iodine-125 3Immunoglobulin G 3Etoposide 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
NIH × Astrocytoma × Radiotherapy, Intensity-Modulated × Clear all
NCT06860594 2026-06-05

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

National Cancer Institute (NCI)

Phase 1 Suspended
30 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT01189266 2021-10-28

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

National Cancer Institute (NCI)

Phase 1/2 Completed
79 enrolled 17 charts
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Gliosarcoma

NCT01514201 2019-08-13

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

National Cancer Institute (NCI)

Phase 1/2 Completed
66 enrolled 24 charts
CNSSarcoma

Astrocytoma, Glioblastoma, Gliosarcoma

NCT01119599 2015-09-29

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
22 enrolled
CNSSarcoma

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroma, Acoustic, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

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