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Phase

Phase 2 20Phase 1 17Phase 3 11Phase 1/2 5Phase NA 3Phase EARLY_PHASE1 2Phase 2/3 2

Status

Withdrawn 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Esophageal Squamous Cell Carcinoma 6Leukemia 5Esophageal Neoplasms 5Rectal Neoplasms 3Lymphoma 3Head and Neck Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Prostatic Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Oropharyngeal Neoplasms 2Oligodendroglioma 2Nasopharyngeal Carcinoma 2Myelodysplastic Syndromes 2Lung Neoplasms 2Leukemia, T-Cell 2Leukemia, Myeloid, Chronic-Phase 2Leukemia, Myeloid, Acute 2Leukemia, Myeloid, Accelerated Phase 2Carcinoma 2Astrocytoma 2Anemia, Refractory, with Excess of Blasts 2Adenocarcinoma Of Esophagus 2Uterine Cervical Neoplasms 1Stomach Neoplasms 1Sezary Syndrome 1Sarcoma, Synovial 1Sarcoma, Ewing 1

Interventions

Temozolomide 3vocimagene amiretrorepvec 2Radiotherapy 2Lomustine 2Bevacizumab 2Vorinostat 1Vincristine 1Radiation 1Procarbazine 1Immunoglobulin G 1Flucytosine 1Disulfides 1DNA 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Astrocytoma × Radiotherapy × Clear all
NCT04105374 2026-05-07

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

NRG Oncology

Phase 2/3 Withdrawn
CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT00003375 2024-07-09

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Radiation Therapy Oncology Group

Phase 2/3 Completed
370 enrolled
CNS

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

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