Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Not yet recruiting 1Enrolling by invitation 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Lymphoid 1

Conditions

Burkitt Lymphoma 14Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Meningeal Carcinomatosis 7Lung Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Breast Neoplasms 6Lymphoma, Large B-Cell, Diffuse 5Leukemia, Myeloid, Acute 5Leukemia, Biphenotypic, Acute 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myelodysplastic Syndromes 3Glioblastoma 3Astrocytoma 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2Neoplastic Cells, Circulating 2Meningeal Neoplasms 2Lymphoma, Mantle-Cell 2Lymphoma, B-Cell 2Lymphoma 2Glioma 2Brain Neoplasms 2Vomiting 1Uveal Melanoma 1Rhabdomyosarcoma 1Psychomotor Agitation 1Pain, Postoperative 1Oligodendroglioma 1Nevus 1Neoplasm Recurrence, Local 1Multiple Myeloma 1

Interventions

Temozolomide 115Radiotherapy 63Magnetic Resonance Spectroscopy 30Carboplatin 30Bevacizumab 30Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 18Lomustine 17Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Astrocytoma × Spinal Puncture × Clear all
NCT03919071 2026-05-27

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
58 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Mayo Clinic

Phase 1/2 Not yet recruiting
33 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT06896110 2025-06-26

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

University of Iowa

Phase 1 Enrolling by invitation
34 enrolled
CNS

Astrocytoma, Glioblastoma

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