Announcements Trials
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Phase

Phase 1 2Phase 3 1Phase 2 1

Status

Completed 2Withdrawn 1Unknown 1

Sponsor Class

OTHER 3NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 1

Conditions

Leukemia, Myeloid, Acute 10Brain Neoplasms 8Myelodysplastic Syndromes 7Neoplasm Metastasis 6Leukemia, Lymphocytic, Chronic, B-Cell 6Glioblastoma 6Recurrence 5Lymphoma 5Glioma 5Sarcoma 4Leukemia 4Head and Neck Neoplasms 4Colorectal Neoplasms 4Astrocytoma 4Ovarian Neoplasms 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Breast Neoplasms 3Uveal Melanoma 2Uterine Cervical Neoplasms 2Thyroid Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Neoplasms, Neuroepithelial 2Nasopharyngeal Carcinoma 2Mouth Neoplasms 2Melanoma 2Medulloblastoma 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2

Interventions

Temozolomide 115Radiotherapy 63Magnetic Resonance Spectroscopy 30Carboplatin 30Bevacizumab 30Carmustine 28Filgrastim 23Surgical Procedures, Operative 22Irinotecan 22Radiation 18Lomustine 17Vincristine 15Etoposide 15Specimen Handling 13Peripheral Blood Stem Cell Transplantation 13O(6)-benzylguanine 13Radiotherapy, Intensity-Modulated 12Procarbazine 11Erlotinib Hydrochloride 11Cyclophosphamide 11Chemotherapy, Adjuvant 11sargramostim 10Thiotepa 10Cisplatin 10Flucytosine 9Everolimus 9antineoplaston AS 2-1 8antineoplaston A10 8Granulocyte Colony-Stimulating Factor 8Vorinostat 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Astrocytoma × Valproic Acid × Clear all
NCT03243461 2022-06-06

HIT-HGG-2013

University of Göttingen

Phase 3 Unknown
167 enrolled
CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Baylor College of Medicine

Phase 2 Completed
38 enrolled 53 charts
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT01861990 2015-05-22

Valproic Acid in Childhood Progressive Brain Tumors

Medical University of South Carolina

Phase 1 Withdrawn
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Children's Oncology Group

Phase 1 Completed
26 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

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