Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2CNS 2

Conditions

Melanoma 3Sarcoma 2Ovarian Neoplasms 2Oligodendroglioma 2Neoplasm Metastasis 2Gliosarcoma 2Glioblastoma 2Fallopian Tube Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Ovarian Epithelial 2Brain Neoplasms 2Astrocytoma 2Uveal Melanoma 1Urinary Bladder Neoplasms 1Urethral Neoplasms 1Unspecified Childhood Solid Tumor, Protocol Specific 1Thyroid Neoplasms 1Thyroid Cancer, Papillary 1Somatostatinoma 1Small Cell Lung Carcinoma 1Rectal Neoplasms 1Neoplasms 1Myeloproliferative Disorders 1Multiple Myeloma 1Multiple Endocrine Neoplasia Type 1 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Glioma 1Fibrolamellar hepatocellular carcinoma 1Endometrial Neoplasms 1

Interventions

Temozolomide 22Radiotherapy 17Carmustine 9Magnetic Resonance Spectroscopy 8Carboplatin 8Vorinostat 6Surgical Procedures, Operative 6Radiation 6Cisplatin 6Chemotherapy, Adjuvant 6O(6)-benzylguanine 5Erlotinib Hydrochloride 5Cyclophosphamide 5Bevacizumab 5veliparib 4Vincristine 4Thiotepa 4Specimen Handling 4Radiotherapy, Intensity-Modulated 4Peripheral Blood Stem Cell Transplantation 4Methotrexate 4Lenalidomide 4Filgrastim 42,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 4Radiotherapy, Conformal 3Procarbazine 3Lomustine 3Iodine-125 3Immunoglobulin G 3Etoposide 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Astrocytoma × aflibercept × Clear all
NCT00369590 2015-10-02

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

National Cancer Institute (NCI)

Phase 2 Completed
58 enrolled 12 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT00650923 2014-05-30

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
61 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

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