Clinical Trials Browser

Phase 1/2 × Terminated × Astrocytoma × Clear all

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT03330197 2025-08-12

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Phase 1/2 Terminated

6 enrolled 14 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT05737212 2025-02-21

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

Phase 1/2 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT00788125 2023-07-14

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Phase 1/2 Terminated

7 enrolled 9 charts

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Burkitt Lymphoma, Carcinoma, Renal Cell, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Spinal Cord Neoplasms, Teratoma, Testicular Neoplasms, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Nephroma, Mesoblastic, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT01721577 2023-05-22

AXL1717

Phase 1/2 Terminated

10 enrolled 8 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01884740 2022-08-09

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Phase 1/2 Terminated

13 enrolled 6 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01044966 2019-02-12

A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

12 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT01189240 2015-12-14

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Phase 1/2 Terminated

13 enrolled 13 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT00021229 2014-07-31

Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma

Phase 1/2 Terminated

85 enrolled 17 charts

Astrocytoma, Central Nervous System Neoplasms

NCT00074334 2009-10-21

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

Phase 1/2 Terminated

Familial ependymoma, Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms