Clinical Trials

37 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

36 enrolled

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07089641 2026-04-07

ERAS801-SARG

10 enrolled

Astrocytoma

NCT05789394 2026-04-02

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy

Astrocytoma, Glioblastoma

NCT07417761 2026-04-02

TUVASTRAT

56 enrolled

Astrocytoma

NCT05839379 2026-03-31

Targeted Pediatric High-Grade Glioma Therapy

350 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03596086 2026-03-30

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

62 enrolled

Astrocytoma, Glioblastoma

NCT03603405 2026-03-30

HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

62 enrolled

Astrocytoma, Glioblastoma

NCT05843253 2026-03-20

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

120 enrolled

Phase EARLY_PHASE1 Recruiting

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06333899 2026-03-12

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

15 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT03896568 2026-03-05

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

36 enrolled

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT05345002 2026-02-20

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

55 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT05957679 2026-02-12

MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Meningioma, Neurofibroma, Spinal Cord Neoplasms

NCT04923126 2026-02-04

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

132 enrolled

Astrocytoma, Ganglioneuroma, Oligodendroglioma, Neoplasms, Neuroepithelial, Ganglioglioma, Neurocytoma

NCT05683808 2026-01-30

VTE-POG

40 enrolled

CNSClassical hematology

Astrocytoma, Glioblastoma, Glioma, Venous Thromboembolism

NCT05084430 2026-01-22

Study of Pembrolizumab and M032 (NSC 733972)

28 enrolled

Astrocytoma, Glioblastoma, Recurrence, Gliosarcoma

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

40 enrolled

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT04065776 2026-01-07

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

74 enrolled

Astrocytoma, Glioma, Ganglioglioma

NCT05686798 2025-12-16

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

18 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT05956821 2025-12-08

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Oligodendroglioma

NCT07223034 2025-11-04

A Study of 177Lu-PSMA-617 in People With Gliomas

Astrocytoma, Glioblastoma, Glioma

NCT05532397 2025-09-23

Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma

10 enrolled

Astrocytoma

NCT06776250 2025-09-19

Study of How Safe and Effective Tarlatamab is in Brain Cancers

44 enrolled

Astrocytoma

NCT06989086 2025-09-09

FearLess in NeuroOncology

112 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma

NCT07159607 2025-09-08

APPEAR

100 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT04188535 2025-08-26

RELAY

CNSGastrointestinalGenitourinaryGynecologic

149 enrolled

Astrocytoma, Esophageal Neoplasms, Glioblastoma, Prostatic Neoplasms, Vulvar Neoplasms

NCT05180825 2025-08-08

PLGG - MEKTRIC

134 enrolled

Phase EARLY_PHASE1 Recruiting

Astrocytoma

NCT04135807 2025-07-23

Implantable Microdevice In Primary Brain Tumors

12 enrolled

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT04780009 2025-07-09

Loupe-Based Intraoperative Fluorescence Imaging

30 enrolled

Astrocytoma, Glioblastoma

NCT06108206 2025-07-03

Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT06815029 2025-06-26

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

27 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT06264388 2025-05-29

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

33 enrolled

Astrocytoma, Glioma

NCT05698524 2025-05-20

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

24 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT06975332 2025-05-16

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression

35 enrolled

Astrocytoma, Glioblastoma

NCT01269853 2025-04-09

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

54 enrolled

Astrocytoma, Glioblastoma, Neoplasms

NCT06915649 2025-04-08

Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach

3,504 enrolled

Hippocampal Sclerosis, Astrocytoma, Epidermal Cyst, Hamartoma, Ganglioglioma, Hemangioma, Capillary, Malformations of Cortical Development

NCT06797661 2025-02-19

NVUCVR

40 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT05190172 2025-02-12

PRO-GLIO

225 enrolled

Astrocytoma, Oligodendroglioma

NCT04648462 2024-11-26

Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology

1,500 enrolled