Announcements Trials
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Phase

Phase 2 2

Status

Terminated 1Completed 1

Sponsor Class

NIH 2INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Melanoma 8Multiple Myeloma 6Hematologic Neoplasms 6Lymphoma 5Neoplasm Metastasis 4Thyroid Neoplasms 2Glioma 2Cholangiocarcinoma 2Carcinoma, Non-Small-Cell Lung 2Carcinoma, Hepatocellular 2Breast Neoplasms 2Bile Duct Neoplasms 2Uveal Melanoma 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Thyroid Cancer, Papillary 1Stomach Neoplasms 1Rectal Neoplasms 1Prostatic Neoplasms 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neurofibromatosis 1 1Lung Neoplasms 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myeloid, Acute 1Klatskin Tumor 1Hemangioendothelioma, Epithelioid 1Glioblastoma 1

Interventions

Oxaliplatin 5Leucovorin 5Capecitabine 5Fluorouracil 4Erlotinib Hydrochloride 4Trastuzumab 3trametinib 2pembrolizumab 2Sorafenib 2N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl-6-(5-((methylsulfonyl)ethyl)aminomethyl)-2-furyl)-4-quinazolinamine 2Lapatinib 2Interleukin-12 Subunit p35 2Gemcitabine 2Floxuridine 2Chemotherapy, Adjuvant 2AZD 6244 2tremelimumab 1tivozanib 1tipifarnib 1motexafin lutetium 1ixabepilone 1entinostat 1durvalumab 1dehydroftorafur 1cediranib 1Watchful Waiting 1Specimen Handling 1Radiotherapy 1Radiofrequency Ablation 1Phototherapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Bile Duct Neoplasms × trametinib × Clear all
NCT04566133 2023-08-21

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
2 enrolled 9 charts
Gastrointestinal

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma

NCT02042443 2017-09-12

S1310

National Cancer Institute (NCI)

Phase 2 Completed
53 enrolled 13 charts
Gastrointestinal

Bile Duct Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Cholangiocarcinoma, Klatskin Tumor

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